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Completed

NCT Number: NCT01133197

The Impact of Thumb Carpometacarpal Osteoarthritis on General Health

This study is designed to define the impact of thumb arthritis on patient's general health. As a secondary objective, data will be analyzed to determine the effects of medical and musculoskeletal comorbidities on the rating of upper extremity function by the patient.

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Key information

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Barnes Jewish Hospital

St Louis, Missouri, 63110, United States

About this study

This study is designed to define the impact of thumb arthritis on patient's general health. As a secondary objective, data will be analyzed to determine the effects of medical and musculoskeletal comorbidities on the rating of upper extremity function by the patient.

Potential Contribution: The data that we intend to gather could further our understanding of the overall health impact of thumb osteoarthritis and allow surgeons to more accurately interpret patient-rated measures of upper extremity function in the presence of comorbidities.

Osteoarthritis of the thumb carpometacarpal joint is one of the most common sites of arthritic degeneration in the hand. To date, no study has examined this conditions impact on overall health using a validated health measure (e.g. SF-36). Additionally, no study has examined the impact of medical and musculoskeletal comorbidities on patient-rated measures of upper extremity function in these patients.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy adults clinically diagnosed with thumb carpometacarpal osteoarthritis. The diagnosis must have been confirmed radiographically prior to consideration for study enrollment.
  • Adults accompanying patients to participating offices will be recruited to be control subjects. They must not be receiving medical or surgical treatment for a hand or wrist complaint.
  • Additionally control subjects must not have been diagnosed with thumb osteoarthritis.

Exclusion criteria

  • Subjects must be over 18 years of age and English speaking.
  • Subjects are not to include incarcerated adults or those unable to provide consent for study participation.
  • Patients diagnosed with currently symptomatic hand or wrist pathology outside of the thumb carpometacarpal joint will be excluded.
  • Patient with prior surgery on the affected thumb will be excluded.
  • Pregnant females are excluded from study participation with pregnancy determined by patient self-reporting (standard of care before office radiographs).

Treatment and study plan

Primary outcomes

  1. Hand Function

    Time frame: Baseline

    Use of hand by Michigan Hand Questionnaire

Secondary outcomes

  1. Overall Health

    Time frame: Baseline

    SF-36

Sponsors and collaborators

Lead sponsor

Washington University School of Medicine

Other

Collaborators

  • University of Rochester

Registry information

Important dates

Study start
2009
Primary completion
2015
Study completion
2015
First posted
May 28, 2010
Registry last updated
Jun 29, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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