Clinical Hospital on Yauza
Moscow, 111033, Russia
Location status: Recruiting
Location contact
Levan Berikashvili, PhD
CONTACT
Levan Berikashvili, PhD
PRINCIPAL_INVESTIGATOR
Sergey Stepanenko
SUB_INVESTIGATOR
NCT Number: NCT05487053
Total knee replacement (TKR) is considered the most effective and safe method of radical treatment of late stages of knee osteoarthritis. A well-known problem of TKR is a severe postoperative pain syndrome, which is observed in more than 50% of patients.
Femoral nerve block (FNB) is the "gold standard" for continuous postoperative analgesia after total knee replacement, as it is effective in reducing the frequency of use of opioid analgetics and reduce the duration of hospitalization. At the same time, the negative effect of this method is the motor blockade of the quadriceps femoris muscle which leads to functional impairment and is associated with an increased risk of falling.
Adductor canal block (ACB) provides adequate analgesia comparable to femoral nerve block. Moreover, ACB doesn't affect the motor function of the quadriceps femoris muscle.
The possibility of enhanced recovery after total knee replacement is the reason to compare single-shot adductor canal block and continuous femoral nerve block.
Interested in participating?
Request Info18 year and older
All sexes
Interventional
Not applicable
Moscow, 111033, Russia
Location status: Recruiting
Levan Berikashvili, PhD
CONTACT
Levan Berikashvili, PhD
PRINCIPAL_INVESTIGATOR
Sergey Stepanenko
SUB_INVESTIGATOR
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Postoperative analgesia in this group will be carried out by a single-shot bolus of 20 ml Ropivacaine 0.5% in the region of the middle third of the adductor canal.
Postoperative analgesia in this group will be carried out by continuous infusion of local anesthetics through a catheter installed to the femoral nerve in the area of the femoral triangle. Ropivacaine 0.2% solution will be used for postoperative analgesia. Local anesthetic infusion rate is 4 ml/h to 10 ml/h.
Time frame: postoperative day 1
Less meters means worse outcome
Time frame: postoperative day 2
Less meters means worse outcome
Time frame: postoperative day 1
More seconds means worse outcome
Time frame: postoperative day 2
More seconds means worse outcome
Time frame: postoperative day 1
More seconds means worse outcome
Time frame: postoperative day 2
More seconds means worse outcome
Time frame: postoperative day 1
Less exercise done means worse outcome
Time frame: postoperative day 2
Less exercise done means worse outcome
Time frame: postoperative day 1
More seconds means worse outcome
Time frame: postoperative day 2
More seconds means worse outcome
Time frame: 30 day
time from the day of surgery to the day of readiness to discharge
Time frame: 30 day
time from the day of surgery to the day of discharge
Time frame: 30 day
frequency of intravascular local anesthetic injection
Time frame: 30 day
frequency of neuropathy after the procedure
Contact information is provided by the study sponsor or research team.
Levan Berikashvili
CONTACT
Valery Likhvantsev
CONTACT
Negovsky Reanimatology Research Institute
Other Gov
The Impact of Single-shot Adductor Canal Block Versus Continuous Femoral Nerve Block on Rehabilitation After Total Knee Replacement (AdORe - ACB)
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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