The Impact of Opioids in Coronary Heart Disease

In this study, the risk of opioid medications on coronary heart disease in adults is investigated. Patients with the necessity of a coronary angiography and control patients with a non-cardiac disease of the same hospital are inquired with a standardized questionnaire about demographic and clinical risk factors for heart attack. An impact of opioid medications on coronary heart disease is hypothesised (MIOP).

In addition, all patients with coronary angiography should be consulted twice (after 3 and 6 months) to find out how many of these patients have developed a refractory angina pectoris (TRAPS).

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Key information

Conditions

Coronary Heart Disease Cardiovascular Diseases Coronary Disease Heart Diseases Myocardial Ischemia Vascular Diseases

Age range

40 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Bergmannsheil department of pain therapy

Bochum, North Rhine-Westphalia, 44789, Germany

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

40 years or older
written informed consent

Exclusion criteria

currently cancer
cognitive limitations

Treatment and study plan

Primary outcomes

Number of patients with opioid treatment (WHO II/ WHO III) within the last 10 years before present hospitalization, Interview with standardized CRF

Time frame: 20 minutes

Standardized assessment of opioid medications taken before hospital admission to evaluate the impact of opioids in coronary heart disease.

Exact doses, substances and intake habits are inquired.
Number of patients with refractory angina pectoris, Interview with standardized CRF

Time frame: 30 minutes

Standardized assessment of angina pectoris symptoms and treatments to evaluate a refractory angina pectoris.

Changes of their medications are inquired twice.

Sponsors and collaborators

Lead sponsor

Ruhr University of Bochum

Other

Collaborators

Mundipharma Research GmbH & Co KG

Registry information

Official study title

Evaluation of Past Medications in Patients With Coronary Heart Disease and Patients Hospitalized for a Non-cardiac Reason

Acronym: MIOP/TRAPS

Important dates

Study start: 2016
Primary completion: 2017
Study completion: 2017
First posted: Apr 15, 2016
Registry last updated: Apr 11, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed