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NCT Number: NCT06403540

The Impact of Laparotomy and Analgesia Methods on Diaphragm

Major abdominal surgeries are traditionally performed via laparotomy. Analgesia is routinely administered during the postoperative period. The goal is to investigate the effects of laparotomy and analgesia methods on diaphragm function.

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Key information

Conditions

Colorectal Neoplasms Colonic Diseases Digestive System Diseases Digestive System Neoplasms Gastrectomy Gastrointestinal Diseases Gastrointestinal Neoplasms Intestinal Diseases Intestinal Neoplasms Neoplasms Neoplasms by Site Rectal Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Prof. Dr. Cemil Taşcıoğlu City Hospital

Istanbul, Turkey (Türkiye)

Location status: Recruiting

Location contact

fethi gültop, m.d.

CONTACT

[email protected]

+905052260067

About this study

Laparotomy is typically performed through a midline incision during major abdominal surgeries. Patients have difficulty breathing deeply after surgery, particularly because of pain. Intravenous drug administration, epidural catheter placement, and abdominal plane blocks are common methods of analgesia. In this study, the investigators will measure the diaphragm muscle thickness at the xiphoid level at the anterior axillary line in the supine position in participants who underwent laparotomy before and one hour after the operation, using ultrasonography M mode during inspiration, expiration, and forced inspiration. the investigators will test the effects of analgesia methods on diaphragm contraction in participants undergoing laparotomy.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • over 18 years,
  • major abdominal surgery cases

Exclusion criteria

  • body mass index (BMI) >35 kg/m2
  • illiteracy,
  • communication issues,
  • neuromuscular disorders,
  • Advanced chronic respiratory disease,
  • Previous abdominal or thoracic surgery

Treatment and study plan

ultrasonography

Diagnostic Test

Using ultrasonography to measure diaphragm thickness

Primary outcomes

  1. The impact of laparotomy on diaphragm thickness.

    Time frame: Measurement at the 1st postoperative hour

    Comparison of diaphragm muscle measurements before and after surgery

Secondary outcomes

  1. The effect of analgesia methods on diaphragm thickness in patients undergoing laparoscopic surgery.

    Time frame: Measurement at the 1st postoperative hour

    Comparison of diaphragm muscle measurements before and after surgery

Study contacts

Contact information is provided by the study sponsor or research team.

fethi gültop

CONTACT

[email protected]

+905052260067

Sponsors and collaborators

Lead sponsor

Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization

Other

Registry information

Official study title

The Impact of Laparotomy and Analgesia Methods on Postoperative Diaphragm Muscle Contraction in Major Abdominal Surgeries.

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
May 8, 2024
Registry last updated
Apr 30, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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