The Impact of Intraoperative Systemic Lidocaine Infusion on Chronic Postoperative Pain After Video-assisted Thoracic Surgery (VATS)

Systemic lidocaine infusion may improve the patients' chronic post surgical pain after video-assisted thoracic surgery

Completed

Looking for future studies?

Key information

Conditions

Lung Cancer(Primary, Metastatic) Benign Lung Mass Requiring Operation Neoplasm Metastasis Neoplasms Neoplastic Processes Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Signs and Symptoms

Age range

20 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institue, Yonsei Universiy College of Medicine

Seoul, 120-752, South Korea

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age between 20 and 65 years
ASA class 1 and 2
Patients who are scheduled for video-assisted thoracic surgery

Exclusion criteria

Allergy to local anesthetics or contraindication to use of lidocaine
Pregnancy
Severe cardiovascular disease
Renal failure
Liver failure
Neurologic and psychologic disease
Chronic treatment with analgesics or chronic pain patients
Previous history of thoracic surgery (open or video-assisted)
Patients' refusal

Treatment and study plan

Systemic intravenous lidocaine infusion

Drug

In group L, intravenous lidocaine infusion(0.1mg/kg) for 10minutes after induction of anesthesia. After 10 minutes, lidocaine infusion continued at rate of 3mg/kg/hr during operation, and discontinued before move the patients to PACU.

Normal saline infusion

Drug

In group C, the patients receive same volume of normal saline

Primary outcomes

Assessing pain score after operation

Time frame: 2 months after operation

Assessing pain score by Short-form McGill pain questionnaire at 2 months after operation

Sponsors and collaborators

Lead sponsor

Yonsei University

Other

Registry information

Important dates

Study start: 2014
Primary completion: 2016
Study completion: 2016
First posted: Dec 10, 2013
Registry last updated: Apr 1, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed