The Impact of Good Versus Poor Sleep Quality on Quality of Life, Depression, and Fatigue in Individuals With Multiple Sclerosis

This cross-sectional study was conducted to examine the effects of good and poor sleep quality on quality of life, depression, and fatigue in individuals with multiple sclerosis.

The study was conducted at the Multiple Sclerosis (n=121) Outpatient Clinic of the Health Research and Application Center at the Trakya University between July 15, 2025, and December 30, 2025, with patients who were receiving outpatient treatment, had no communication difficulties, and agreed to participate in the study. These patients were provided with an "Informed Consent Form" "Pittsburgh Sleep Quality Index," "SF-12 Quality of Life Scale," "Beck Depression Scale," and "Fatigue Impact Scale." Participants were informed about the purpose of the study, and if they agreed to participate, they were asked to complete the questionnaire forms.

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Key information

Conditions

Quality of Life Autoimmune Diseases Autoimmune Diseases of the Nervous System Behavior Behavioral Symptoms Demyelinating Autoimmune Diseases, CNS Demyelinating Diseases Depression Dyssomnias Fatigue Immune System Diseases Mental Disorders Multiple Sclerosis Nervous System Diseases Pathological Conditions, Signs and Symptoms Signs and Symptoms Sleep Disorders, Intrinsic Sleep Initiation and Maintenance Disorders Sleep Wake Disorders

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Trakya University Faculty of Medicine Dean'S Office Building

Merkez, Edirne, 22100, Turkey (Türkiye)

About this study

Sleep disorders are common among individuals with multiple sclerosis and negatively impact their physical and psychological well-being. This study was conducted to examine the effects of good and poor sleep quality on quality of life, depression, and fatigue in individuals with multiple sclerosis.

Material and Methods: The study was conducted between july 15, 2025 and December 30, 2025 with 121 patients diagnosed with Multiple Sclerosis at the Neurology outpatient clinic of a university hospital in Edirne. Data were collected using "Patient Information Form" "Pittsburgh Sleep Quality Index," "SF-12 Quality of Life Scale," "Beck Depression Scale," and "Fatigue Impact Scale." Participants were informed about the purpose of the study, and if they agreed to participate, they were asked to complete the questionnaire forms.

Financial Support: The present study was supported by the Research Fund of Trakya University. Project No: 2025/278

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Being over 18 years of age
Having a confirmed diagnosis of multiple sclerosis
Being a registered patient at a multiple sclerosis clinic
Not experiencing communication difficulties
Volunteering to participate in the study

Exclusion criteria

Being under 18 years of age
Not having a confirmed diagnosis of multiple sclerosis
Not currently attending a multiple sclerosis clinic
Experiencing communication difficulties
Not volunteering to participate in the study

Treatment and study plan

Primary outcomes

determining sleep quality

Time frame: 6 month

To evaluate the association between sleep quality and quality of life, depression, and fatigue in individuals with multiple sclerosis.

Sponsors and collaborators

Lead sponsor

Trakya University

Other

Registry information

Official study title

Multiple Sklerozlu Bireylerde Iyi Uyku Kalitesi ve kötü Uyku Kalitesinin yaşam Kalitesi, Depresyon ve Yorgunluk üzerine Etkisi

Important dates

Study start: 2025
Primary completion: 2025
Study completion: 2026
First posted: Jul 2, 2026
Registry last updated: Jul 2, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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