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Completed

NCT Number: NCT02788838

The Impact of Food Advertisements on Brain Response and Eating Behavior in Children

The purpose of this project is to examine the impact that television food advertisements have on brain responses and eating behavior in children. Food advertisements enhance children's liking and intake of foods that tend to be high in energy content and low in nutritional value. Although several studies have measured the differences in children's food intake after watching advertisements, none have shown the brain mechanisms associated with this change in behavior. In order to clarify the relationship between food advertising and eating behavior, the investigators have assembled a team with expertise in functional imaging, eating behaviors, and clinical pediatric research. First, the investigators will observe the differences in children's eating behaviors after being exposed to food commercials or non-food commercials. Second, the investigators will measure the difference in child brain response to high and low energy foods after being exposed to food commercials or non-food commercials. These data will allow us to identify which areas of the brain are specifically affected by exposure to food commercials and correlate activity in these areas with children's measured food intake in the laboratory. Children ages 7-9 will participate in this 5-visit study which will be completed over the course of 12 months. Understanding how food advertisements impact children's brain responses and subsequent eating behaviors will have implications for understanding why some children respond differently to these cues than others. These outcomes may also inform the development of more effective programs and policies to prevent childhood obesity.

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Key information

Age range

7 year–9 year

Sex eligibility

All sexes

Study type

Observational

Primary location

The Pennsylvania State University

University Park, Pennsylvania, 16802, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Right-handed
  • English as native language
  • Reading at/above grade level
  • Not Claustrophobic
  • Generally Healthy

Exclusion criteria

  • Left-handedness
  • Metal in or on body that cannot be removed
  • Claustrophobic
  • Medication usage that may alter brain activity or blood flow
  • Medical disorder that may impact comfort or safety in MRI scanner
  • Food allergies

Treatment and study plan

Primary outcomes

  1. Functional magnetic resonance imaging (fMRI), blood oxygen level dependent (BOLD) response to high and low energy foods following food commercial priming

    Time frame: Collected at fMRI scan at week 4 or 5 (randomized)

    Whole-brain response to food images varied by 2 levels of energy viewed in 2 conditions

  2. Functional magnetic resonance imaging, blood oxygen level dependent (BOLD) response to high and low energy foods following toy commercial priming

    Time frame: Collected at fMRI scan at week 4 or 5 (randomized)

    Energy intake of foods consumed ad libitum at each laboratory test-meal in 3 conditions

  3. Baseline Energy Intake

    Time frame: Collected at week 1 of the study

    Energy intake of foods consumed ad libitum at laboratory test-meal with no priming stimulus

  4. Energy Intake following food commercials

    Time frame: Collected at week 2 or 3 (randomized) of the study

    Energy intake of foods consumed ad libitum at laboratory test-meal following food commercials priming

  5. Energy Intake following toy commercials

    Time frame: Collected at week 2 or 3 (randomized) of the study

    Energy intake of foods consumed ad libitum at laboratory test-meal following toy priming stimulus

Secondary outcomes

  1. Region of Interest (ROI)-response to food type by condition

    Time frame: Collected at fMRI scans at weeks 4 and 5 of study

    Response in selected regions of interest to images varied by 2 levels of energy viewed in 2 conditions

Other outcomes

  1. Appetitive traits

    Time frame: Collected at week 1

    Parent-reported questionnaire of habitual eating styles in children

  2. Television and Internet use and exposure

    Time frame: Collected at week 1

    Parent and child reported questionnaires of television and internet use and exposure to shows and commercials

  3. BMI-z score

    Time frame: Collected at week 1

    BMI-z score calculated using age, sex, weight, and height

  4. Liking and Wanting of Foods

    Time frame: Collected at week 1

    Ratings to how much child likes and wants specific foods used in the test meals on child friendly computerized rating scale

  5. Pubertal Development

    Time frame: Collected at week 1

    Parent reported pubertal development through questionnaire

  6. Parental feeding strategies

    Time frame: Collected at week 1

    Parent-reported measures of feeding practices

  7. Height

    Time frame: Collected at week 1

    Height in cm measured by stadiometer

  8. Weight

    Time frame: Collected at week 1

    Weight in kg measured by standard digital scale

  9. Body Fat Percentage

    Time frame: Collected at week 1

    Body Fat Percentage assessed by Bio Electrical Impedance Scale

  10. BMI

    Time frame: Collected at week 1

    Calculated from height and weight (kg/m^2)

Sponsors and collaborators

Lead sponsor

Penn State University

Other

Registry information

Important dates

Study start
2016
Primary completion
2017
Study completion
2017
First posted
Jun 2, 2016
Registry last updated
Jan 13, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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