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Completed

NCT Number: NCT05587179

The Impact of Different Recovery Positions on the Perfusion of the Lower Forearm and Comfort

Introduction: A side-lying recovery position is recommended when victims are unresponsive but breathing normally and, hence, do not require cardiopulmonary resuscitation. In 2021, the European Resuscitation Council (ERC) and the Belgian Red Cross-Flanders issued new guidelines which included the description of a modified recovery position to avoid problems in victims with joint stiffness and to overcome potential obstructed venous return in the dependent arm. Based on good practice insights, the dependent arm will now be extended and not bent to support the other arm. However, there is currently no evidence available to support a specific recovery position.

Objectives: The aim of this study is to assess the impact of different recovery positions on perfusion of the forearm and associated comfort.

Methods: In this cross-over randomized controlled trial, 24 healthy volunteers will be placed in either the lateral recovery position with extended dependent arm or with bent arm, and in the other position thereafter. Before and between both recovery positions, the volunteers will be positioned supine for 15 min. Several perfusion indices of the forearm will be non-or mildly invasively monitored in the respective recovery positions by radial artery tonometry, ulnar artery echo doppler and venous congestion plethysmography. Subjective participant's discomfort and pain will be assessed as well. Differences in continuous outcomes between the different recovery positions will be assessed with paired t-tests or wilcoxon signed-rank test.

Discussion: The benefit of lateral positioning of adults and children with decreased level of consciousness has been widely accepted despite limited supportive scientific evidence. We here will provide direct evidence (i) whether venous drainage in the dependent limb is impaired when positioning the victim in the lateral recovery position with bent arms and (ii) whether this potential complication can be minimized by extending the dependent arm. The major limitations of this study is that healthy volunteers, instead of non-responsive victims, are included as participants, and that the study will be performed in a highly controlled environment. Nevertheless, the generated insights will directly fuel evidence-based treatment recommendations regarding the recovery position in first aid settings, and fill a current gap in evidence.

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Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Antwerp University Hospital

Edegem, Antwerp, 2650, Belgium

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

-healthy volunteers

Exclusion criteria

  • History of any coronary or peripheral vascular disease such as Raynaud's disease or thromboangitis obliterans (self-declared)
  • Type I or type II diabetes (self-declared)
  • Intake of cholesterol-lowering medication (self-declared)
  • High blood pressure (systolic blood pressure > 140 mmHg and/or diastolic blood pressure > 90 mmHg) and/or use of antihypertensive drugs (self-declared)
  • Obesity (BMI > 30 kg/m2)
  • Smoking or using tobacco products (self-declared)

Treatment and study plan

recovery position

Other

A side-lying recovery position is a first aid intervention that can be performed by laypeople when victims are unresponsive but breathing normally and, hence, do not require cardiopulmonary resuscitation.

Primary outcomes

  1. Difference in peripheral arterial pressure (PAP)

    Time frame: between 10 to 15 min in each position

    extracted from pulse wave amplitude (PWA) measured by radial artery tonometry

  2. Cross-sectional area of the ulnar artery (SU) and peak systolic velocity of the ulnar artery (PSVU) of the hand of the dependent arm

    Time frame: between 10 to 15 min in each position

    measured by echo doppler

  3. Peripheral venous pressure (PVP)

    Time frame: between 10 to 15 min in each position

    measured at the forearm and the back of the hand by venous congestion plethysmography

Secondary outcomes

  1. Oxygen saturation

    Time frame: measured continuously during 1u15 min (15 min supine position, 15 min posture 1, 15 min supine position, 15 min posture 2, 15 min supine position)

  2. Heart rate

    Time frame: measured continuously during 1u15min (15 min supine position, 15 min posture 1, 15 min supine position, 15 min posture 2, 15 min supine position)

  3. Discomfort (experienced by participant)

    Time frame: after 15 min in the recovery position

    10-point Likert-scale completed by the participants

  4. Pain (experienced by participant)

    Time frame: after 15 min in the recovery position

    10-point Likert-scale completed by the participants

  5. Skin discoloration

    Time frame: after 15 min in the recovery position

    10-point Likert-scale completed by the researcher

Sponsors and collaborators

Lead sponsor

Centre for Evidence-Based Practice, Belgium

Other

Collaborators

  • University Hospital, Antwerp

Registry information

Official study title

The Impact of Different Recovery Positions on the Perfusion of the Lower Forearm and Comfort Associated With the Positioning: a Cross-over Randomized Controlled Trial

Important dates

Study start
2022
Primary completion
2023
Study completion
2023
First posted
Oct 19, 2022
Registry last updated
Jan 29, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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