Outdoor track and field facility of Xuzhou Medical University
Xuzhou, Jiangsu, 221000, China
NCT Number: NCT06338449
The purpose of this clinical trial is to investigate which exercise regimen is more effective in improving non-alcoholic fatty liver disease (NAFLD) in a young population. The primary questions it aims to answer are:
Does aerobic training, resistance training, or a combination of both help improve liver function and glycemic and lipid parameters in NAFLD patients? Which of these three exercise regimens is more effective in improving the aforementioned parameters? Is the improvement in liver function related to bile acid metabolism?
Participants will:
Engage in physical exercise 4-5 times per week for two consecutive months, following a predefined exercise regimen.
Have blood samples collected to test for glucose, lipids, liver function, and other parameters before starting the exercise program and after two months of completing the regimen.
Looking for future studies?
Notify Me18 year–23 year
All sexes
Interventional
Not applicable
Xuzhou, Jiangsu, 221000, China
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
An exercise program was developed by a full-time physical education teacher, with all group exercises conducted at the outdoor track and field facility of Xuzhou Medical University. Participants in the aerobic training group, after completing a warm-up, were required to perform moderate-intensity aerobic running for 60 minutes per session, 4-5 times a week. The exercise intensity was set to reach 50%-70% of the maximum heart rate (Maximum heart rate = 220 - age). The exercise sessions were scheduled in the evening after dinner, from 17:30 to 19:00.All participants were continuously intervened for 8 weeks.
Participants in the resistance training group were required to complete moderate-intensity resistance exercises 4-5 times per week. Each session included a warm-up, followed by exercises such as knee lifts with torso twists, knee-to-hand taps under the hips, jumping jacks, burpees, sit-ups, planks, and squats. The routine was structured to perform 5-6 exercises per session, with 6-8 repetitions for each set. There was a 30-second rest interval between sets, and the total exercise time was 60 minutes. The timing for these exercise sessions was the same as for the AT group, conducted in the evening after dinner.All participants were continuously intervened for 8 weeks.
Participants in the combined aerobic and resistance training (AT+RT) group started their sessions with a warm-up, followed by 30 minutes of aerobic running. After the aerobic training, they engaged in resistance training. The resistance training regimen was the same as that for the RT group, except that the duration of the resistance training was shorter. The total duration of the exercise session was 60 minutes.All participants were continuously intervened for 8 weeks.
Time frame: Baseline and 8 weeks
Time frame: Baseline and 8 weeks
BMI
Time frame: Baseline and 8 weeks
Time frame: Baseline and 8 weeks
Time frame: Baseline and 8 weeks
Time frame: Baseline and 8 weeks
Time frame: Baseline and 8 weeks
Time frame: Baseline and 8 weeks
Time frame: Baseline and 8 weeks
Time frame: Baseline and 8 weeks
Time frame: Baseline and 8 weeks
Time frame: Baseline and 8 weeks
Time frame: Baseline and 8 weeks
Time frame: Baseline and 8 weeks
Time frame: Baseline and 8 weeks
Time frame: Baseline and 8 weeks
Time frame: Baseline and 8 weeks
Time frame: Baseline and 8 weeks
Time frame: Baseline and 8 weeks
Time frame: Baseline and 8 weeks
Xuzhou Medical University
Other
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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