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NCT Number: NCT03577327

The Gut and Skin Microbiome in Vitiligo Disease Progression

Investigators plan to perform a pilot study that aims to characterize the microbiome of human vitiligo patients with both active and stable disease and compare this to the microbiome of age and sex matched controls. The investigators aim to answer the question whether the gut and skin microbiome of patients with vitiligo differs from the general population.

Recruiting

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Key information

Conditions

Vitiligo Healthy Hypopigmentation Pigmentation Disorders Skin Diseases Skin and Connective Tissue Diseases

Age range

18 year–89 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Northwestern University

Chicago, Illinois, 60611, United States

Location status: Recruiting

Location contact

Dermatology CTU

CONTACT

[email protected]

312-503-5944

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with and/or without vitiligo lesional expansion over the past year.
  • Age/sex-matched controls who do not have a diagnosis of vitiligo
  • Subjects who are age 18-89 years of age at time of enrollment
  • Subjects who are able and willing to give informed consent for this study and the Dermatology Tissue Acquisition and Biorepository (STU00009443)

Exclusion criteria

  • Subjects who are younger than 18 years of age or 90 years of age or older
  • Subjects who are unable to give consent

Treatment and study plan

Primary outcomes

  1. Microbiome composition

    Time frame: 12 months

    Diversity analysis of microbiome samples in control subjects versus vitiligo subjects (measured by number of bacteria species/sample)

  2. Disease Progression

    Time frame: 12 months

    Disease progression in control subjects versus vitiligo subjects (measured by VASI score (0-100)).

Secondary outcomes

  1. Diet History Food Frequencies

    Time frame: 12 months

    Scoring from diet history food frequency questionnaires (measured by average daily food frequency scores).

Study contacts

Contact information is provided by the study sponsor or research team.

Dermatology CTU

CONTACT

[email protected]

312-503-5944

Sponsors and collaborators

Lead sponsor

Northwestern University

Other

Registry information

Important dates

Study start
2019
Primary completion
2026
Study completion
2026
First posted
Jul 5, 2018
Registry last updated
Jun 9, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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