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NCT Number: NCT03381794

The German Keratoplasty Registry of the German Ophthalmological Society (DOG)

Aim of this study is to reflect on the changing trends in absolute numbers, surgical techniques and indications of corneal transplantations being performed in Germany.

The Section Cornea of the German Ophthalmological Society provides interim-assessments on a regular basis about the most up-to-date results of this long-term study.

Recruiting

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Key information

Conditions

Corneal Transplantation

Age range

1 year–100 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

All patients in Germany treated with the different types of corneal transplantation since 2001.

Exclusion criteria

Patients without corneal transplantation.

Treatment and study plan

Corneal transplantation

Procedure

PKP: Penetrating Keratoplasty DALK: Deep Anterior Lamellar Keratoplasty DMEK: Descemet Membrane Endothelial Keratoplasty DSAEK: Descemet's Stripping Automated Endothelial Keratoplasty

Other names: PKP, DALK, DMEK, DSAEK

Primary outcomes

  1. An overview about absolute numbers of corneal transplantation in Germany.

    Time frame: 01/01/2001 to 31/12/2031

    A questionnaire about absolute numbers of corneal transplantation per year was sent to the 111 ophthalmological departments in Germany performing corneal transplantation. Data has been and is collected annually since 2001.

  2. An overview about trends in the various types of corneal transplantation in Germany.

    Time frame: 01/01/2001 to 31/12/2031

    The questionnaire also records the types of corneal transplantation (i.e. penetrating keratoplasty, deep anterior lamellar keratoplasty, Descemet membrane endothelial keratoplasty (DMEK) and Descemet's stripping automated endothelial keratoplasty DSAEK) allowing a discussion of trends in corneal transplantation. Data has been and is collected annually since 2001.

  3. An overview about indications for corneal transplantation in Germany.

    Time frame: 01/01/2001 to 31/12/2031

    The questionnaire also records the indications for corneal transplantation (e.g. Fuchs' endothelial corneal dystrophy, pseudophakic corneal decompensation, repeated keratoplasty after graft failure, keratoconus and corneal scarring). Data has been and is collected annually since 2001.

Study contacts

Contact information is provided by the study sponsor or research team.

Berthold Seitz, Prof.Dr.med.

CONTACT

[email protected]

0049-6841-16-22387

Elias Flockerzi, PD Dr.med.

CONTACT

[email protected]

0049-6841-16-22302

Sponsors and collaborators

Lead sponsor

Universität des Saarlandes

Other

Collaborators

  • Charite University, Berlin, Germany
  • Heinrich-Heine University, Duesseldorf
  • University Eye Hospital, Freiburg
  • University of Cologne
  • University of Erlangen-Nürnberg

Registry information

Official study title

Trends in Corneal Transplantation From 2001 in Germany: Reports of the DOG-Section Cornea and Its Keratoplasty Registry

Important dates

Study start
2001
Primary completion
2036
Study completion
2036
First posted
Dec 22, 2017
Registry last updated
Apr 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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