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NCT Number: NCT03478553

The Genetics of Pulmonary Fibrosis

This study seeks to screen first degree family members of people with Idiopathic Pulmonary Fibrosis (IPF) for the earliest signs of lung fibrosis.

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Key information

Conditions

Idiopathic Pulmonary Fibrosis (IPF) Idiopathic Pulmonary Fibrosis Lung Diseases Lung Diseases, Interstitial Pulmonary Fibrosis Respiratory Tract Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Colorado Anschutz Medical Campus

Aurora, Colorado, 80045, United States

Location status: Recruiting

Location contact

Maria Rodriguez, BA

CONTACT

303-724-0738

Rachel Warren, BA

CONTACT

[email protected]

303-724-8569

About this study

The purpose of this study is to explore genetic factors associated with the development of pulmonary fibrosis. The investigators aim is to identify and explore genetic loci that affect development of pulmonary fibrosis and also explore related environmental exposures. Idiopathic pulmonary fibrosis (IPF) is one of the interstitial lung diseases under the broader umbrella of idiopathic interstitial pneumonias (IIP). The investigators hypothesize that inherited genetic factors are associated with pulmonary fibrosis. To investigate the genetics of pulmonary fibrosis, the investigators plan to enroll individuals with pulmonary fibrosis and their family members.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age at least 18 years old
  • Family member diagnosed with IPF

Exclusion criteria

  • No family member with IPF

Treatment and study plan

Blood Draw

Other

Blood draw

Questionnaire

Other

Pulmonary Fibrosis Questionnaire

Primary outcomes

  1. Identify and explore genetic loci and related environmental exposures in individuals with familial pulmonary fibrosis and their relatives.

    Time frame: Baseline

    The investigators aim is to identify and explore genetic loci that affect development of pulmonary fibrosis and also explore related environmental exposures. Idiopathic pulmonary fibrosis (IPF) is one of the interstitial lung diseases under the broader umbrella of idiopathic interstitial pneumonias (IIP). The investigators hypothesize that inherited genetic factors are associated with pulmonary fibrosis.

Study contacts

Contact information is provided by the study sponsor or research team.

Rachel Warren

CONTACT

[email protected]

303-724-8569

Sponsors and collaborators

Lead sponsor

University of Colorado, Denver

Other

Registry information

Official study title

Idiopathic Pulmonary Fibrosis, a Disease Initiated by Mucociliary Dysfunction

Important dates

Study start
2018
Primary completion
2026
Study completion
2026
First posted
Mar 27, 2018
Registry last updated
Mar 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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