Skip to main content
OpenTrials
Recruiting

NCT Number: NCT06445660

The Feasibility of a Radiological Score Based on CT Signs for Recognizing Salvageable Bowel in Acute Mesenteric Ischemia

Computed tomography (CT) is the standard modality for scanning patients with critical acute abdominal conditions, including suspected acute mesenteric ischemia (AMI). CT imaging can potentially differentiate between reversible and irreversible ischaemic damage of the bowel. This moment is pivotal in selecting the treatment strategy for AMI - in the absence of irreversible damage; reperfusion therapy can preserve intestinal viability, thereby avoiding the need for bowel resection. The present study tests the hypothesis that combining several symptoms may enhance the diagnostic performance of CT scanning in detecting salvageable bowel in patients with AMI. This study is an ancillary component of the AMESI study (Clinical Trials: NCT05218863) - a prospective, multicentre observational study aimed at identifying the incidence and describing the outcomes of acute mesenteric ischemia (AMI) in adult hospitalized patients. The ultimate purpose of the present study is to create a computed tomography-based radiological score for the assessment of bowel viability in patients with AMI.

Recruiting

Interested in participating?

Request Info

Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Tartu University Hospital

Tartu, 50408, Estonia

Location status: Recruiting

Location contact

Martin Reim, Dr

CONTACT

[email protected]

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Participant in AMESI study
  • confirmed or suspected acute mesenteric ischaemia
  • CT scan of the entire abdominal cavity / full body using intravenous contrast media is available

Exclusion criteria

  • Scans without the use of an intravenous contrast media or those covering only a partial area of the abdomen will be excluded.

Treatment and study plan

Primary outcomes

  1. Frequency rate

    Time frame: up to one month

    Frequency rate of common radiological signs in AMI patients with and without salvageable bowel.

Secondary outcomes

  1. Performance of the radiological score

    Time frame: up to one month

    Performance of the radiological score in patients with different types of AMI.

Study contacts

Contact information is provided by the study sponsor or research team.

Joel Starkopf

CONTACT

[email protected]

53318400 ext. 372

Kätlin Eiche

CONTACT

[email protected]

Sponsors and collaborators

Lead sponsor

University of Tartu

Other

Registry information

Official study title

The Feasibility of a Radiological Score Based on Quantified Analysis of Computed Tomography Signs for Recognizing Salvageable Bowel in Acute Mesenteric Ischemia: A Retrospective Analysis of Prospective Study

Acronym: AMESIradiol

Important dates

Study start
2022
Primary completion
2023
Study completion
2025
First posted
Jun 6, 2024
Registry last updated
Mar 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.