University of Pittsburgh
Pittsburgh, Pennsylvania, 15260, United States
NCT Number: NCT01799772
Patients who undergo a replacement of their knees are generally older adults who have dealt with severe knee pain and joint degeneration for a long time. The majority of them are sedentary, and around 1/3 are obese. The knee replacement surgery decreases knee pain and helps patients to live a better life. However, after the surgery, some patients have difficulty performing basic activities such as walking, or going up-down stairs, and the majority remains sedentary and gain weight. These combined problems leave patients at risk of worsening their health. Therefore, a treatment that takes care of all these combined problems is needed. We propose an all-inclusive treatment, called comprehensive behavioral intervention (CBI) that intends to improve the long-term effects of exercise programs. The CBI combines exercise program with promotion of physical activity, orientation on healthy nutrition, and an education approach that promotes self-initiative towards healthy habits. The overall aim of this proposed study is to test how patients post TKA will like the CBI program, how safe the program is, and adapt the program as needed for better acceptability. We believe the CBI will be safe, well tolerated, and will improve the ability of patients to perform physical tasks. We also believe the program will increase the amount of physical activity, will promote maintenance of healthy weight, and will help the patients to obtain and maintain healthy habits. In this study subjects will be selected by a flip of a coin to receive either our CBI program or a more traditional exercise program. Subjects will be tested before and after the treatments. Our measures of main interest are how well subjects move around and how physically active they are. We are also interested on the effect of the interventions on body weight, blood pressure, eating habits, and general health. The team of researchers for this study includes several disciplines. The proposed study will defend the need for a larger study that can have a very important impact on the public health of patients post TKA. The reason for the public health impact is if the physical limitations experiences by patients post TKA are left untreated, they tend to get worse. Furthermore, by increasing physical activity and promoting healthy weight, it may improve general health and prevent chronic diseases. Last, developing educational intervention that promotes self-initiative will result in long-term health benefits post TKA.
Looking for future studies?
Notify Me50 year and older
All sexes
Interventional
Phase 1 / Phase 2
Pittsburgh, Pennsylvania, 15260, United States
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Typical rehabilitation after TKA surgery
Time frame: 6 months
Change from Baseline in Western Ontario and McMaster Universities Osteoarthritis Index - Physical Function scale (WOMAC-PF) at 6 months.
Time frame: 6 months
Change from Baseline in Self-selected gait speed at 6 months.
Time frame: 6 months
Change from Baseline in Timed 5 chair rise at 6 months.
Time frame: 6 months
Change from Baseline in single leg balance time at 6 months.
Time frame: 6 months
Change from Baseline in timed ascend/descend stair test at 6 months.
Time frame: 6 months
Change from Baseline in 6 minutes walk test at 6 months.
Time frame: 6 months
Change from Baseline in measures of physical activity taken by a portable activity monitor at 6 months.
Time frame: 6 months
Change from Baseline in the Medical Outcomes Survey 36-Item Short-Form Health Survey at 6 months.
Time frame: 6 months
Change from Baseline in measures of physical activity taken by a self-reported questionnaire (CHAMPS) at 6 months.
University of Pittsburgh
Other
The Feasibility of a Comprehensive Behavioral Intervention in Patient Post Total Knee Arthroplasty
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