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Completed

NCT Number: NCT03078387

The Extreme Significance of Bilateral Embolic Retinal Phenomena That Can be Life Saving

This study shows how careful ophthalmic examination of two patients showed signs of simultaneous bilateral retinal emboli. Starting from this point significant, life threatening, underlying reasons were found and treated.

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Key information

Conditions

Life Threatening Diseases Embolic Shower

Age range

30 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Dr. S.S. Michel Clinic

Edmonton, Alberta, T5R5W9, Canada

About this study

Two patients were found to have signs of simultaneous bilateral retinal emboli. One patient was asymptomatic and routine ophthalmic examination showed bilateral retinal hemorrhages and exudates close to both optic discs. This patient was on anti-coagulant treatment for atrial fibrillation. The finding of bilateral signs of retinal emboli necessitated immediate blood tests and dose adjustments of her medication.

The second case did not have general symptoms other than mild evening chills and her eye examination again was the start point of intensive investigation to find the reason of her bilateral retinal emboli. Ultrasound studies revealed a life threatening reason that was urgently treated.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • any patient who is found to have sure signs of bilateral retinal emboli.

Exclusion criteria

  • all other bilateral retinal diseases.

Treatment and study plan

Imaging

Diagnostic Test

imaging before and after treatment

Other names: color fundus photos

Primary outcomes

  1. The extreme significance of immediate investigation of cases of bilateral retinal emboli (non-diabetic bilateral posterior pole retinal nerve fiber or pre-retinal hemorrhages).

    Time frame: through study completion, an average of one year

    Patients that are noticed to have signs of bilateral retinal emboli (bilateral retinal nerve fiber layer hemorrhages or bilateral pre-retinal hemorrhages and sometimes bilateral soft exudates) may be asymptomatic or have very mild symptoms. However these patients must be immediately and, if needed, intensively investigated to find the source of these emboli. The extremely important point of this study is these patients usually have life threatening conditions that should be found out and treated in time.

Sponsors and collaborators

Lead sponsor

Dr. Shawkat Michel

Other

Registry information

Official study title

Bilateral Retinal Embolic Phenomena Always Necessitates Immediate and Intensive Investigation. Careful, Documented, Ophthalmic Examination is All we Require to Initiate Life Saving Investigations.

Important dates

Study start
2006
Primary completion
2013
Study completion
2018
First posted
Mar 13, 2017
Registry last updated
Apr 4, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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