Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT06867133

The Evaluation of the Curative Effect of Electrophysiological Rehabilitation Services on Endometrial Repair After Induced Abortion

Exploring the efficacy evaluation of electrophysiological rehabilitation services in endometrial repair after induced abortion, providing scientific basis for medical institutions and government post abortion care decision-making.

This study is a multicenter randomized controlled intervention study. The main endpoint of the study was the measurement of endometrial thickness by transvaginal ultrasound on days 21-23 after abortion.

Secondary study endpoint:

1. Postoperative uterine contraction pain; 2. Patient satisfaction; 3. Menstrual recurrence time; 4. Changes in menstrual flow for two consecutive periods after surgery; 5. The duration of two consecutive menstrual periods after surgery.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Conditions

Endometrium

Age range

18 year–40 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Female aged 18-40 years old;
  • Previous menstrual patterns;
  • Pregnancy duration 6-10 weeks;
  • Ultrasound indicates intrauterine pregnancy;
  • Voluntarily accepting surgical induced abortion with no contraindications for induced abortion;
  • Voluntarily participate in the trial and sign the informed consent form.
  • Patients or their families are able to understand the research protocol and are willing to participate in this study, providing written informed consent.

Exclusion criteria

  • Medical abortion patients;
  • Patients with pelvic and abdominal benign and malignant tumors and other systemic diseases; C) Skin problems such as ulceration, infection, and blisters at the treatment site;

d) Patients with missed miscarriage diagnosed clinically; e) Patients with combined uterine fibroids, adenomyosis, and uterine malformations; f) Those who have inserted intrauterine devices (including copper containing intrauterine devices and levonorgestrel containing intrauterine devices); g) Individuals who have had three or more previous induced abortions; h) Clinical diagnosis of thin endometrium; i) Individuals with a history of cesarean section surgery; j) Individuals with severe mental illnesses; k) Researchers determine other situations that are not suitable for participating in this study; l) Patients or their families are unable to understand the conditions and objectives of this study.

Treatment and study plan

Electrophysiological rehabilitation

Device

On the basis of treatment in the control group, postoperative electrophysiological rehabilitation services were started for 30 minutes each time, once a day, for 6 consecutive days as one course of treatment, for a total of one course of treatment. The patch is located at the projection site of the lower abdomen uterus as shown in the figure, simulating bioelectric stimulation parameters: biphasic pulse current, frequency 2Hz, pulse width 3ms.

Simultaneously conducting family health education, including but not limited to:

  • Guidance on postoperative physical recovery after abortion: provide advice on postoperative care, nutrition, activity, and personal hygiene;
  • Introduction to contraceptive methods: Introduce the advantages and disadvantages of various contraceptive methods, and help patients choose the most suitable contraceptive method for themselves;
  • Other related health education: including fertility planning and the best time to conceive again.

Primary outcomes

  1. Transvaginal ultrasound examination is used to measure the thickness of the endometrium.

    Time frame: On the 21st to 23rd day after abortion.

    On the 21st to 23rd day after abortion, vaginal ultrasound was used to measure endometrial thickness.

Secondary outcomes

  1. Postoperative uterine contraction pain

    Time frame: One week after surgery

    The degree of postoperative pain was evaluated using the Visual Analogue Scale (VAS) scoring method. A horizontal line of 10 cm in length was drawn, with the two ends representing 0 and 10 respectively. 0 indicated no pain, and 10 represented the most unbearable pain that could be imagined. Patients were asked to select the corresponding number based on their postoperative pain sensation to describe the intensity of their subjective pain. The time for postoperative pain assessment was as follows: for the experimental group, the VAS pain score was evaluated before treatment on the second day after surgery and after one session of bioelectrical stimulation treatment; for the control group, the VAS pain score was evaluated only once on the second day after surgery.

  2. Patient satisfaction

    Time frame: 3 months after surgery

    Survey the satisfaction levels of patients in the control group and intervention group, specifically covering sub item satisfaction evaluations of biomimetic electrical stimulation treatment, doctor attitude, abortion process, and extended home rehabilitation services. Each item is divided into five levels: very satisfied, satisfied, average, dissatisfied, and very dissatisfied. In addition, the overall satisfaction of the above four items will be comprehensively evaluated.

  3. Menstrual recurrence time

    Time frame: 3 months after surgery

    Observe the time of menstrual recurrence in two groups after surgery, that is, the interval between the completion of induced abortion and the recurrence of menstruation in the subjects.

  4. Changes in menstrual flow for two consecutive periods after surgery

    Time frame: 3 months after surgery

    Understand the postoperative menstrual flow of the research subjects for two consecutive periods. The specific reference criteria are: compared with the preoperative menstrual flow, it is divided into five levels: much more, slightly more, similar, slightly less, and much less.

  5. Duration of two consecutive menstrual periods after surgery

    Time frame: 3 months after surgery

    By conducting a 3-month online follow-up on the control group and intervention group, we aim to understand the duration of continuous menstruation in the study subjects after surgery.

Study contacts

Contact information is provided by the study sponsor or research team.

Xinyan Liu， Ph.D

CONTACT

[email protected]

+86 186 0000 8013

Sponsors and collaborators

Lead sponsor

Peking Union Medical College Hospital

Other

Registry information

Acronym: rehabilitation

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Mar 10, 2025
Registry last updated
Mar 10, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.