The Efficacy of White Kidney Bean on Oral Glucose Tolerance Test

Inclusion criteria

• Healthy adults aged 25-45 years, with a male to female ratio of more than 40% and BMI 24.

35 subjects enrolled and 30 subjects completed the study;

• There is no history of diabetes and other metabolic syndrome, digestive diseases, endocrine disorder and mental diseases;
• No history of food allergy and intolerance;
• No nutritional supplements that affect glucose tolerance, oral contraceptives, acetylsalicylic acid, steroids, protease inhibitors, and antipsychotic drugs in the past 3 months;
• Able to tolerate at least 10 hours of fasting;
• Willing to refrain from participating in other interventional clinical studies during the trial period;
• Be able to fully understand the purpose, benefits and potential risks including side effects of the research;
• Willing to obey all test requirements and procedures;
• Informed consent signed.

Exclusion criteria

• Subject who is in the treatment of gastrointestinal diseases;
• Subjects are currently suffering from other organic diseases that affect intestinal function, such as history of gastrointestinal resection, colonic or rectal cancer, inflammatory bowel disease, diabetes, hyperthyroidism or hypothyroidism, Hirschsprung's disease, scleroderma, anorexia nervosa, etc.;
• Controlling diet, exercising, or taking medications to control weight or affect appetite in the last 3 months;
• Subjects have any of the following medical history or have been clinically examined to have the following diseases that may affect the evaluation of the test effect: obvious gastrointestinal dysfunction, liver, kidney, endocrine, blood, respiratory and cardiovascular diseases;
• Abuse alcohol or other drugs, supplement or OTC drugs currently or n the past may cause bowel dysfunction or can affect test result evaluation;
• Frequently use of medications that may affect gastrointestinal function or the immune system according to investigator's judgment;
• Take laxatives or other substances that promote digestion 2 weeks before the trail start;
• Pregnant or lactating women or those planning to become pregnant during the trial;
• Liver function tests (alanine aminotransferase and aspartate aminotransferase), renal function tests (blood urea nitrogen and creatinine), routine blood tests, urinalysis, fecal occult blood test or electrocardiogram abnormalities.