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NCT Number: NCT06785649

The Efficacy of Lavender Herbal Tea in Misophonia

Misophonia is a disorder characterized by a high level of annoyance with certain sounds. Exposure to these sounds causes physical symptoms characterized by anger, aggression, helplessness, overwhelm, and stimulation of the sympathetic nervous system. These emotional and physical reactions can lead to a decline in family relationships, work and school productivity, withdrawal from social relationships, and even suicide. There is limited empirical evidence evaluating the efficacy of therapeutic approaches to misophonia. This limited empirical evidence consists of pharmacological agents such as selective serotonin reuptake inhibitors, stimulants, antipsychotics, and β-Blockers, as well as cognitive behavioral therapy, acceptance and commitment therapy, and dialectical behavior therapy. Complementary therapies are important because of their potential efficacy, tolerability, possible non-interference, and low cost. The fact that lavender has anxiolytic, antidepressant, neuroprotective, and anti-inflammatory properties may affect the emotional and physical responses elicited by misophonia. Therefore, within the scope of the study, misophonia individuals will be divided into two groups; one group will use lavender tea for 14 days and the other group will form a waiting list. The study data will be collected by 'Information Collection Form', 'Misophonia Scale', 'Beck Depression Inventory-II', 'Anxiety Rating Scale', and 'Trait Anger Scale'. SPSS 25.0 software will be used to analyze the data obtained from the research. Considering the limitations of therapeutic approaches for misophonia, testing the effectiveness of lavender in reducing misophonia symptoms will make an important contribution to the literature.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

Misophonia is a disorder of vocal sensitivity characterized by unusual discomfort with certain sounds. Typical triggers are sounds produced by humans, particularly oral and nasal sounds. These sounds include chewing, slurping, breathing, keyboard sounds, or pen clicks. When individuals with misophonia are exposed to triggers, stimulation of the sympathetic nervous system and emotional distress are observed. Exposure to triggers creates irritation, desire to avoid stimuli, anger, aggression, helplessness, and overwhelm. Stimulation of the sympathetic nervous system leads to physical symptoms such as hypertonia, sweating, and tachycardia. The discomfort and stress caused by misophonia can lead to increased anxiety levels in individuals. At the same time, the emotional distress and discomfort associated with misophonia can trigger depressive symptoms and increase the risk of depression. Concomitant anxiety and depression can worsen the existing symptoms of misophonia and lead to a reduced quality of life.

There is limited empirical evidence evaluating the efficacy of therapeutic approaches to misophonia. Current treatment approaches include cognitive behavioral therapy, acceptance and commitment therapy, and psychotherapies derived from dialectical behavior therapy. Due to the small number of randomized controlled trials, the efficacy of the protocols used in the treatment of misophonia remains unclear. Due to limited resources, problems such as limited access to psychotherapies and early withdrawal from treatment are also observed. Other treatment approaches include pharmacological agents such as selective serotonin reuptake inhibitors (SSRIs), stimulants, antipsychotics, and β-Blockers. Complementary therapies are used due to their potential efficacy, tolerability, possible non-interference, and low cost. Lavender, a complementary treatment intervention, is considered to have anxiolytic, antidepressant, neuroprotective, and anti-inflammatory properties. Lavender is known to positively affect memory, provide alertness, and improve feelings of well-being. Thus, it is seen as an effective herbal medicine intervention in reducing anxiety and depression. Reducing concomitant anxiety and depression may contribute to the improvement of the symptoms of misophonia.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Reporting at least three trigger sounds
  • Assessed by a specialist psychiatric nurse and a psychiatrist as humophonia based on the diagnostic criteria for humophonia established by Schröder et al. (2013)
  • Individuals aged 18 and over

Exclusion criteria

  • Allergy to any herbal tea, food or medicine
  • Psychiatric illness or chronic illness
  • Taking psychiatric medication (such as anxiolytics, and antidepressants)
  • Regular use of medication (such as antihypertensive, antidiabetic)
  • Regular use of herbal teas or complementary medicines
  • Tinnitus and/or hyperacusis

Treatment and study plan

Lavender herbal tea

Other

The participant will be allocated 14 pieces of lavender tea bags consisting of 2 grams and originating from Turkey. During 14 days, the participant will be advised to use 2 g of lavender herb brewed in 300 mL hot water for 10-15 minutes in the morning and evening. Participants will be able to use 1 lavender tea bag twice a day.

Primary outcomes

  1. Misophonia Scale

    Time frame: Within the first 24 hours after 14 days of lavender tea

    It is a 30-item self-report scale aiming to assess the severity of misophonia. The scale is a 5-point Likert-type scale and is graded between 1: Strongly agree and 5: Strongly disagree to 5: Strongly disagree. The total score range is 30 - 150. As the score obtained from the scale decreases, the level of misophonia severity decreases.

Secondary outcomes

  1. Beck Depression Inventory-II (BDI-II)

    Time frame: Within the first 24 hours after 14 days of lavender tea

    It is a 21-item self-report inventory aimed at assessing the severity of depression. The items are rated from 0 to 3 depending on the severity of symptoms. The total score range is 0 to 63 and is divided into four grades in terms of severity: minimal depression (total score 0-13), mild depression (14-19), moderate depression (20-28) and severe depression (≥ 29).

  2. Anxiety Assessment Scale

    Time frame: Within the first 24 hours after 14 days of lavender tea

    This scale, which evaluates anxiety, consists of 10 items. The scale is in 5-point Likert type and is expressed as 1: Never, 2: Very Rarely, 3: Sometimes, 4: Often, 5: Almost Always. There are no reverse scored items in the scale, the total scale score of anxiety is obtained by summing all items. The lowest score that can be obtained from the scale is 10 and the highest score is 50. The higher the total score, the higher the level of anxiety.

  3. Trait Anger Scale (SL-Anger)

    Time frame: Within the first 24 hours after 14 days of lavender tea

    This scale is an assessment tool that measures how often and at what level individuals feel anger in their lives. Consisting of 10 items, this test is graded with a four-point Likert type (1=Never, 2=Sometimes, 3=Most of the time, 4=Always). The increase in the total score obtained from the scale indicates that the individual tends to feel anger more frequently and more intensely in his/her life.

Study contacts

Contact information is provided by the study sponsor or research team.

Gülgün Durat, PhD

CONTACT

[email protected]

0264 295 66 12

Sevgi Koroglu, MSc

CONTACT

[email protected]

05367982320

Sponsors and collaborators

Lead sponsor

Sakarya University

Other

Registry information

Official study title

The Effect of Lavender Herbal Tea on the Mental Health of Individuals With Misophonia: A Randomized Clinical Trial

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jan 21, 2025
Registry last updated
Jan 21, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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