Oncolgy Center, Mansoura University,
Al Mansurah, DK, 53316, Egypt
NCT Number: NCT03269890
Thyroid gland surgery is one of the most commonly performed operations for either benign or malignant pathologies Pain related to thyroid surgery is of moderate intensity .which may be treated with NSAIDs or opioids. However, Opioids have many well-known undesirable effects, including postoperative nausea and vomiting, which are frequent after this type of procedure.
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Notify Me20 year–60 year
All sexes
Interventional
Not applicable
Al Mansurah, DK, 53316, Egypt
Regional techniques of anesthesia may help to decrease post-operative pain and reduce systemic analgesic requirement. Classically, the cervical plexus is considered to have two distributions, the superficial cutaneous and the deep motor nerves.
Anatomically, the thyroid gland has an inner true capsule which is thin and adheres closely to the thyroidal tissue [Fancy et al., 2010]. External to this is a false capsule formed by the middle layer of the deep cervical fascia, which splits anterolaterally to ensheathe the thyroid gland, thus forming the thyroid sheath [Bliss et al., 2000]. In this fashion, the potential space called the capsule-sheath space is formed. It contains also loose connective tissue, blood vessels, nerves and parathyroid gland. Anesthetic deposited in this space would block the surface of thyroid gland and permeate directly into the parenchyma producing effective local anesthesia for thyroid surgical procedures. It is supposed also to involve autonomic nerve block of the thyroid gland [Fliers et al., 2010]. Additionally, a subcutaneous injection along the sternocleidomastoid muscle (SCM) would also enhance effective local anesthesia for the initial skin incision and further contribute to a more ideal working environment for the surgeon. Therefore, anesthetic technique termed ultrasound-guided capsule-sheath space block (CSSB) combined with anterior cervical cutaneous nerves block (CCNB) for thyroidectomy is done [Wang et al., 2015] .
Our hypothesis is that a combination of simple dual techniques including superficial cutaneous block to provide sensory blockade, and surgeon mediated capsular block may afford autonomic thyroid blockade. In comparison, ultrasound guided intermediate cervical plexus block may provide these blocks but using a machine and deep penetration possibly involving unwanted blocks for phrenic and recurrent laryngeal nerves. So, if the simple safe technique can provide the same intra and postoperative anesthetic conditions it will be preferred.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
7.5 mL of 0.5% bupivacaine + Epinephrine 5 ug/ ml for both blocks once before surgery per side
15 mL of 0.5% bupivacaine + Epinephrine 5 ug/ ml once before surgery per side.
Time frame: For 24 hours after surgery
The total dose of opioid analgesics required in the post-operative periods
Time frame: For 24 hours after surgery
Postoperative visual analogue score (VAS) (0 no pain -10 worst imaginable pain),
Time frame: For 24 hours after surgery
Time to first request for a rescue analgesic
Time frame: For 5 hours after start of anaesthesia
Intraoperative use of fentanyl
Time frame: For 5 hours after start of anaesthesia
Intraoperative use of rocuronium
Time frame: for 1 hour after surgery
Assessment of sensory blockade
Time frame: for 5 hours after performing blockade
Diaphragmatic dysfunction using ultrasound assessment and possible x ray
Time frame: for 5 hours after performing blockade
Sedation score using Modified Ramsay scale
Time frame: for 24 hrs after surgery
Patient satisfaction regards analgesia using a score of (0-10) with 10 represents the highest satisfaction
Time frame: For 24 hours after surgery
frequency
Time frame: For 24 hours after surgery
frequency
Time frame: For 24 hours after surgery
frequency
Time frame: For 24 hours after surgery
frequency
Time frame: For 24 hours after surgery
Peripheral oxygen saturation less than 92%
Mansoura University
Other
The Efficacy of Intermediate Cervical Plexus Block Versus Cutaneous and Thyroid Capsular Blocks in Thyroid Surgeries
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