Recruiting

NCT Number: NCT06535867

The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Malignant Disorders and Oral Cancer Amongst the Rural Population of Varanasi: A Prospective and Blinded Study

Mobile health (mHealth) will be used for early detection of oral cancer and pre-cancer lesions, and to improve awareness of oral cancer among the population and knowledge of oral cancer diagnosis among frontline health providers. This program is inclusive of long term surveillance to downstage oral cancer in India

Recruiting

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Key information

Conditions

Smoking Alcohol Drinking Behavior Betel Chewer's Mucosa Cigarette Smoking Drinking Behavior Smokeless Tobacco Hyperkeratosis Smoking, Cigarette Smoking, Tobacco Tobacco Smoking Tobacco Use

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Memorial Sloan Kettering Cancer Center (All protocol activites)

New York, 10065, United States

Location status: Recruiting

Location contact

Milind Rajadhyaksha, PhD

CONTACT

646-608-2364

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Positive for any one or more of the following:

All individuals aged above 18 years positive for habits (smoking and smokeless tobacco, chewing betel leaf, areca nut, paan masala, and/or regular use of alcohol)
Clinical signs/symptoms (non-healing ulcers, white/ red/red & white patches in the mouth, restriction of mouth opening and swelling of the neck)
All individuals aged above 40 irrespective of habit/oral lesions

Exclusion criteria

Individuals already diagnosed with oral cancer and undergoing treatment for oral cancer
Under treatment for tuberculosis or suffering from any acute illness/ debilitating systemic disorders

Treatment and study plan

mHealth

Diagnostic Test

The mobile health (mHealth) program will be used for early detection of oral cancer and pre-cancer lesions, and to improve awareness of oral cancer among the population and knowledge of oral cancer diagnosis among frontline health providers.

Other names: Mobile Health

Primary outcomes

Comparison of mHealth with conventional oral cancer screening

Time frame: Up to 5 years

To compare the efficacy of conventional screening with mHealth in identification of oral potentially malignant disorders (OPMDs) / oral cancer.

Study contacts

Contact information is provided by the study sponsor or research team.

Aditi Sahu

CONTACT

[email protected]

646-608-1935

Milind Rajadhyaksha, PhD

CONTACT

[email protected]

646-608-2364

Sponsors and collaborators

Lead sponsor

Memorial Sloan Kettering Cancer Center

Other

Registry information

Important dates

Study start: 2024
Primary completion: 2031
Study completion: 2031
First posted: Aug 2, 2024
Registry last updated: May 22, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Recruiting