Sujittra Kluayhomthong
Khon Kaen, 40002, Thailand
NCT Number: NCT02553200
The efficacy of breathing exercise with oscillated inspiratory loading and oscillated positive expiratory pressure for airway secretion clearance and lung function in intubated patients, both with and without mechanical ventilation dependence
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Interventional
Not applicable
Khon Kaen, 40002, Thailand
Effective strategies to increase mucus clearance rate has been suggested to depend on 4 factors.
Multifunctional breathing device, the BreatheMAX, is the only breathing device made in Thailand. The BreatheMAX device possess many properties or techniques that benefit for respiratory care particularly 3 in 4 mechanisms for secretion clearance. The unique important aspect is the simultaneously providing several beneficial effects in one breath which are 1) Oscillation in the range of ciliary beat frequency 2) Biofeedback of respiratory effort that could encourage the deeper breathing performance, 3) Humidifier of inspired air, 4) Loaded breathing for inspiratory muscle training and generate PEP. These 4 functions would be very useful for increase secretion clearance particularly in more peripheral airway which are the most difficult to be cleared and be a risk of atelectasis and infection in patients with MV whose natural secretion clearance mechanisms are compromised, respiratory muscle weakness weak and low immunity.
Therefore, the combination of inspiratory and expiratory breathing exercise through the BreatheMAX breathing device may increase or promote more secretion clearance and improve lung function than expiratory breathing exercise alone in intubated patients, both with and without mechanical ventilation dependence
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
for 10 breathes/set, 10 sets/day and rest 1 minute between set
for 10 breathes/set, 10 sets/day and rest 1 minute between set
for 10 breathes/set, 10 sets/day and rest 1 minute between set
Time frame: the secretion will be collected between 3 hours before start breathing exercise program and 3 hours after end of breathing exercise program in each day
The mucus secretion will be collected by nursing staff using sterile suctioning technique via tracheostomy (TT) or endotracheal (ET) tube, without adding any saline or sterile water, the timing of suction procedure depend on the secretion sound in the ET and TT tube.
Time frame: within 30 minutes before breathing exercise and 30 minute after breathing exercise
Time frame: within 30 minutes before breathing exercise and 30 minute after breathing exercise
Time frame: within 30 minutes before breathing exercise and 30 minute after breathing exercise
Time frame: within 30 minutes before breathing exercise and 30 minute after breathing exercise
Time frame: within 30 minutes before breathing exercise and 30 minute after breathing exercise
Time frame: within 30 minutes before breathing exercise and 30 minute after breathing exercise
Time frame: 5 minutes before breathing exercise and during breathing exercise and 5 minute after breathing exercise
the data will be recorded every minute
Time frame: 5 minutes before breathing exercise and during breathing exercise and 5 minute after breathing exercise
the data will be recorded every minute
Time frame: 5 minutes before breathing exercise and during breathing exercise and 5 minute after breathing exercise
the data will be recorded every minute
Time frame: 5 minutes before breathing exercise and 5 minute after breathing exercise
Khon Kaen University
Other
Study of Breathing Exercise With Oscillated Inspiratory Loading (OIS) and Oscillated Positive Expiratory Pressure (OPEP) for Airway Secretion Clearance and Lung Function in Intubated Patients, Both With and Without Mechanical Ventilatory Support
Acronym: BMACPF
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.