The Efficacy and Safety of 2.5 mg Chlorhexidine Gluconate Chip (PerioChip®) in Frequent Treatment Versus Routine Treatment in Therapy of Adult Chronic Periodontitis

Inclusion criteria

• Signed and dated Informed Consent Form.
• Good general health.
• Male or female patients aged >21 years old.
• Availability for the 25 week duration of the study.
• Chronic periodontal disease on natural teeth
• Females of childbearing potential must be non-pregnant and non-lactating at entry and agree to use an adequate method of birth control during the study.

Exclusion criteria

• Oral health or factor that may influence the outcome of the study.
• History of allergy to Chlorhexidine .
• Patient uses Chlorhexidine oral rinses/mouthwashes on a regular basis.
• Patients treated with medications that may influence the outcome of the study.
• Presence of any of the following conditions: Type 1 diabetes, un-controlled type II diabetes, major recurrent aphtae stomatitis, abscesses and related oral pathologies.
• The presence of any medical or psychiatric condition or any other condition that, in the opinion of the Investigator, could affect the successful participation of the patient in the study.
• Patient participates in any other clinical study 30 days prior to the start of the study and throughout the study duration.