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Completed

NCT Number: NCT03982251

The Effects of Whole Body Vibration in People With Chronic Stroke

Whole body vibration (WBV) has been found to be useful in promoting bone health and muscle performance in older adults. To date, no study has examined the effects of different WBV frequencies on the properties of the muscle-bone unit in stroke patients. The overall aim of the proposed study is to compare the efficacy of different vibration frequencies on properties of the muscle function and bone turnover among people with chronic stroke.

It is hypothesized that the higher-vibration frequency protocol will lead to significantly better outcomes related to the bone turnover and muscle function.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

The Hong Kong Polytechnic University

Hong Kong

About this study

Whole body vibration (WBV) has been found to be useful in promoting bone health and muscle performance in older adults. To date, no study has examined the effects of different WBV frequencies on the properties of the muscle-bone unit in stroke patients. The overall aim of the proposed study is to compare the efficacy of different vibration frequencies on properties of the muscle function and bone turnover among people with chronic stroke.

It is hypothesized that the higher-vibration frequency protocol will lead to significantly better outcomes related to the bone turnover and muscle function in people with chronic stroke.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • a diagnosis of stroke
  • stroke onset >6 months
  • >18 years of age
  • able to walk for short distance independently with or without walking aid
  • able to understand simple verbal commands

Exclusion criteria

  • neurological conditions other than stroke
  • significant musculoskeletal conditions (e.g. amputations)
  • metal implants in the lower extremity
  • previous fracture of the lower extremity
  • are currently taking bone resorption inhibitors or were taking the same before stroke.
  • significant peripheral vascular disease
  • vestibular disorders
  • pregnancy
  • Other serious illnesses that preclude the person from participating in the study

Treatment and study plan

High frequency whole body vibration

Procedure

1 single session ( 8 minutes) of whole body vibration therapy at 30 Hz

Other names: Whole body vibration therapy (30Hz)

Low frequency whole body vibration

Procedure

1 single session ( 12 minutes) of whole body vibration therapy at 20 Hz

Other names: Whole body vibration therapy (20Hz)

Primary outcomes

  1. bone resorption marker

    Time frame: pre-test (week 0)

    Serum level of aminoterminal crosslinked telopeptide

  2. bone resorption marker

    Time frame: post-test (week8)

    Serum level of aminoterminal crosslinked telopeptide

Secondary outcomes

  1. Six Minute Walk Test

    Time frame: pre-test (week 0)

    endurance test

  2. Six Minute Walk Test

    Time frame: post-test (week8)

    endurance Test

  3. Gait velocity

    Time frame: pre-test (week 0)

    10-meter walking test

  4. Gait velocity

    Time frame: post-test (week8)

    10-meter walking test

  5. Spasticity

    Time frame: pre-test (week 0)

    H-reflex on tibial nerve and modified ashworth scale

  6. Spasticity

    Time frame: post-test (week8)

    H-reflex on tibial nerve and modified ashworth scale

Sponsors and collaborators

Lead sponsor

The Hong Kong Polytechnic University

Other

Registry information

Official study title

The Effects of Whole Body Vibration Training With Different Frequencies on Bone Health and Neuromotor Performance in Individuals With Chronic Stroke: A Randomized Controlled Trial.

Important dates

Study start
2017
Primary completion
2018
Study completion
2018
First posted
Jun 11, 2019
Registry last updated
Jun 11, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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