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Completed

NCT Number: NCT03743922

The Effects of Vitamin D2 Supplement During Pregnancy

The effects of vitamin D2 supplement during pregnancy on postpartum maternal and fetal vitamin D levels: the randomized controlled trial

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Key information

Conditions

Age range

18 year and older

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Rajavithi hospital

Bangkok, Thailand, 10400

About this study

Vitamin D structurally similar to steroids. Made from the skin. And metabolism of the liver, kidneys, vitamin D levels in the bloodstream are two types of vitamin D 2 (Ergocalciferol) and vitamin D 3 (Cholecalciferol) Vitamin D regulates calcium and phosphorus levels in the body. Including the accumulation of minerals in the bone. Vitamin D is important in the formation of bones and teeth and the normal growth of children, affects the reabsorption of amino acids in the kidneys, regulates the amount of calcium and phosphorus in the blood Vitamin D deficiency in pregnant affects the mother and baby example high maternal blood pressure during pregnancy, diabetes during pregnancy, increase birth body weight of baby. low calcium seizures Infants, baby have bones and growth disorders. Currently, no vitamin D supplement is used in pregnant women in Thailand who attend antenatal clinics. The researcher has proposed to study the effects of vitamin D supplement during pregnancy on postpartum maternal and fetal vitamin D levels by using vitamin D 20,000IU / week

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Women who have pregnant and ANC at Rajavithi hospital
  • Women who have age at least 18 year
  • Women who have Thai nationality
  • Women who have pregnant of gestational age under 20week

Exclusion criteria

  • Women who don't plan of delivered at Rajavithi hospital
  • Women who have complication of pregnancy
  • Woman who delivered before gestational age 37week
  • Women who have abnormal kidney function
  • Woman who have been used anticonvulsant drug or others form of vitamin d
  • Women who have vitamin d allergy

Treatment and study plan

Calciferol

Drug

calciferol capsule

Other names: vitimin d2

Placebo

Drug

placebo capsule

Other names: placebo ( for calciferol )

Primary outcomes

  1. effect of vitamin D 2 supplementation during pregnancy

    Time frame: within 30 minute after delivered

    To study the effect of vitamin D 2 supplementation during pregnancy on postpartum maternal and fetal vitamin D levels effects of vitamin D2 supplement during pregnancy on postpartum maternal and fetal vitamin D levels

Secondary outcomes

  1. vitamin D levels in maternal blood during pregnancy

    Time frame: at first time ANC

    To assess vitamin D levels in maternal blood during pregnancy

  2. vitamin D levels in maternal blood after vitamin D supplementation

    Time frame: within 30 minute after delivered

    To assess vitamin D levels in maternal blood after vitamin D supplementation during pregnancy

Sponsors and collaborators

Lead sponsor

Department of Medical Services Ministry of Public Health of Thailand

Other Gov

Registry information

Official study title

The Effects of Vitamin D2 Supplement During Pregnancy on Postpartum Maternal and Fetal Vitamin D Levels: the Randomized Controlled Trial

Important dates

Study start
2018
Primary completion
2018
Study completion
2020
First posted
Nov 16, 2018
Registry last updated
Dec 3, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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