The Effects of Three Oral Medications on Post-operative Pain Following Endodontic Treatment

Aim: eliminating or reducing pain following endodontic treatment is of great importance. The aim of this study is to compare the effects of Tramadol, Novafen and Naproxen on post-operative pain following instrumentation of root canals in teeth with irreversible pulpitis. Sample size: one hundred patients considering the inclusion and exclusion criteria were selected. Intervention and outcome: The effect of Tramadol, Novafen and Naproxen on post-operative pain following instrumentation of root canals in teeth with irreversible pulpitis was evaluated.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Pulpitis Agnosia Dental Pulp Diseases Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations Pain Pain Management Pathological Conditions, Signs and Symptoms Perceptual Disorders Signs and Symptoms Stomatognathic Diseases Tooth Diseases

Age range

20 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1 / Phase 2

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

The subjects were 20-60 years of age with no systemic diseases and females were not pregnant;
No history of taking any analgesics or other drugs prior to presenting for treatment;
Patients had moderate to severe pain associated with irreversible pulpitis in single-rooted premolars or anterior teeth.

Exclusion criteria

Treatment and study plan

Placebo

Drug

Placebo

Tramadol

Drug

Tab, 100mg in 6, 12 and 24 hours after root canal treatment

Novafen

Drug

325 mg in 6, 12 and 24 hours after root canal treatment

Naproxen

Drug

Tab, 500 mg in 6, 12, and 24 hours after root canal treatment

Sponsors and collaborators

Lead sponsor

Azad University of Medical Sciences

Other

Registry information

Important dates

Study start: 2010
Primary completion: 2010
Study completion: 2010
First posted: Aug 10, 2010
Registry last updated: Aug 10, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Not Yet Recruiting