The Effects of Risperidone and Olanzapine on Thinking

The goal of this research is to find ways to maximize the benefits of antipsychotic medications for cognition.

Hypothesis: Risperidone and olanzapine will show greater benefits than conventional medications on assessments of social cognition, particularly affect perception and social perception.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Schizophrenia Mental Disorders Psychotic Disorders Schizophrenia Spectrum and Other Psychotic Disorders

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

VA Greater Los Angeles Healthcare System

Los Angeles, California, 90073, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Diagnosed with schizophrenia disorder by a DSM IV.
Competent to sign informed consent
No history of poor response to Risperdal and Zyprexa
No organic brain disease

Exclusion criteria

Mental retardation or any chronic medical illness which results in the patient not being appropriate for a switch to Risperdal or Zyprexa.

Treatment and study plan

Risperidone

Drug

Olanzapine

Drug

Sponsors and collaborators

Lead sponsor

US Department of Veterans Affairs

Fed

Collaborators

Janssen, LP

Registry information

Official study title

The Cognitive Effects of Risperidone and Olanzapine

Important dates

Study start: 2003
Study completion: 2006
First posted: Apr 15, 2005
Registry last updated: Jan 21, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed