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Completed

NCT Number: NCT04292106

The Effects of Red Spinach Extract Supplementation on Isometric Strength, Resistance Exercise and Cognitive Performance

Red Spinach is a natural food which is a rich source of nitrates, which are beneficial in hemodynamics, cardiovascular function, and have natural hypotensive and antianginal effects. Red spinach extract has been shown to be beneficial in exercise performance, albeit mostly in aerobic exercise. In a previous study in our lab, we found that dietary nitrate consumption resulted in significantly greater isometric force production in teenage males. However, currently there is little know regarding the effects of dietary nitrate supplementation on isometric strength, resistance exercise and cognitive performance.

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Key information

Conditions

Sports

Age range

18 year–34 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Jeremy Townsend

Nashville, Tennessee, 37215, United States

About this study

This research study is designed to measure the effects of red spinach extract (RSE) on markers of physical and cognitive performance during and following anaerobic exercise.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18-34 years old Participants must have at least 1 year of resistance training experience.
  • Free of any physical limitations, medications, and supplements that may affect performance, as determined by a health and activity questionnaire.
  • Are free of musculoskeletal injuries
  • Are not taking medications that may interfere with study measurements

Exclusion criteria

  • Participants that cannot take either the RSE or placebo supplement will be excluded, as this will be a double-blind study.
  • Furthermore, participants that cannot participate in pre- and post-research testing, and/or those that cannot commit to regular training sessions will be excluded.
  • Inability to perform physical exercise (determined by health and activity questionnaire)
  • Taking any other nutritional supplement or performance enhancing drug.
  • Any chronic illness that causes continuous medical care

Treatment and study plan

Red Spinach Extract (RSE)

Dietary Supplement

Oral capsules containing 2g of Red Spinach Extract will be consumed daily for 7 days

Placebo

Dietary Supplement

Oral placebo capsules will be taken consisting of maltodrextrin daily for 7 days

Primary outcomes

  1. Bench Press Repetitions to Fatiuge

    Time frame: Through study completion, during both treatments (~4 weeks)

    Number of repetitions completed in each set during the acute exercise bout will be recorded and analyzed

  2. Bench Press Power

    Time frame: Through study completion, during both treatments (~4 weeks)

    Power during bench press repetitions will be measured via a linear transducer.

  3. Isometric Mid-thigh pull (IMTP) Peak Force

    Time frame: Through study completion, during both treatments (~4 weeks)

    Peak Force will be measured via dual force plates during a full-body isometric strength test.

  4. Isometric Mid-thigh pull (IMTP) Rate of Force Development

    Time frame: Through study completion, during both treatments (~4 weeks)

    Rate of Force development will be measured via dual force plates during a full-body isometric strength test.

Secondary outcomes

  1. Estimated Muscle Blood Flow via Near-infrared Spectroscopy (NIRS)

    Time frame: Through study completion, during both treatments (~4 weeks)

    Measures of muscle oxygenation of the anterior deltoid will be estimated using a NIRS Device.

  2. Cognitive Performance via Stroop Test

    Time frame: Through study completion, during both treatments (~4 weeks)

    The Stroop Color and Word Test (SCWT) is a neuropsychological test used to assess cognitive performance. This will be administered before and after the fatiguing bench press protocol

Sponsors and collaborators

Lead sponsor

Lipscomb University

Other

Registry information

Official study title

The Effects of Red Spinach Extract Supplementation on Isometric Strength, Resistance Exercise and Cognitive Performance.

Important dates

Study start
2019
Primary completion
2020
Study completion
2020
First posted
Mar 2, 2020
Registry last updated
Jan 14, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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