The Effects of Radium-223 Dichloride Therapy on Radionuclide Bone Scan Lesions.

number of lesions specified before and after the treatment with a bone scan

The ECOG scale describes a patient's level of functioning in terms of their ability to care for themself, daily activity, and physical ability (walking, working, etc.). The possible scores on the scale are 0 to 5, with 0 being the best outcome and 5 being the worst outcome, details of each score are listed below.

Grade 0 = Fully active, able to carry on all pre-disease performance without restriction Grade 1 = Restricted in physically strenuous activity but ambulatory and able to carry out work of a light or sedentary nature, e.g., light house work, office work Grade 2 = Ambulatory and capable of all selfcare but unable to carry out any work activities; up and about more than 50% of waking hours Grade 3 = Capable of only limited selfcare; confined to bed or chair more than 50% of waking hours Grade 4 = Completely disabled; cannot carry on any selfcare; totally confined to bed or chair Grade 5 = Dead

As assessed using numeric rating score from 1-10 with 10 being the highest level of pain

normal level should be 4.0 ng/mL. value is measured after each dose

The normal value for alkaline phosphatase is 53 to 128 U/L.

The normal level for males is 14 to 18 g/dl

A normal platelet count ranges from 150,000 to 450,000 platelets

The normal range for neutrophils is 2.5-7.5 x 10 9 /L

Normal levels of creatinine in the blood are approximately 0.6 to 1.2 milligrams (mg) per deciliter (dL)

The typical white blood cell count varies from 4,000 to 10,000 cells per mm3.