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OpenTrials
Completed

NCT Number: NCT00972803

The Effects of Pistacia Mutica on De Novo Dental Plaque Formation, Gingival Inflammation and Oral Microorganisms

Dental plaque is a well known etiologic factor for gingivitis. Recently, herbal extracts are a matter of scientific interest to inhibit plaque accumulation on teeth. The purpose of this study was to evaluate the effects of pistacia Mutica (PM) mouth wash on de novo dental plaque plaque formation, gingival inflammation indices and oral microorganisms.

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Key information

Conditions

Gingivitis Dental Deposits Dental Plaque Gingival Diseases Infections Mouth Diseases Periodontal Diseases Stomatognathic Diseases Tooth Diseases

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Drug Applied Science Center, tabriz Univ. of Medical Sciences

Tabriz, East Azerbaijan Province, Iran

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • had merely gingivitis (pocket depth≤3 mm, no attachment loss)
  • without any fixed or removable oral appliances

Exclusion criteria

  • Individuals who had a history of any relevant systemic diseases
  • Individuals who had a history of any drug usage

Treatment and study plan

pistacia Mutica extract

Drug

The subjects were asked to use a mouthwash containing pistacia Mutica extract twice a day for 4 days.

Placebo

Drug

The subjects were asked to use a placebo mouthwash twice a day for 4 days.

Chlorhexidine

Drug

The subjects were asked to use a mouthwash containing Chlorhexidine twice a day for 4 days.

Primary outcomes

  1. The effects of pistacia Mutica extract (PM) on de novo plaque formation.

    Time frame: In a 4 days experimental periods followed by a 10 days wash-out periods.

Secondary outcomes

  1. staining effects of pistacia Mutica extract in comparison to placebo or Chlorhexidine

    Time frame: In a 4 days experimental periods followed by a 10 days wash-out periods

Sponsors and collaborators

Lead sponsor

Tabriz University

Other

Registry information

Important dates

Study start
2008
Study completion
2009
First posted
Sep 9, 2009
Registry last updated
Sep 9, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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