The Effects of Periodontal Therapy on Glycemic Control in Diabetic Patients

Is the non-surgical periodontal therapy can improve glycemic control in type 2 diabetic patients with chronic periodontitis?

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Key information

Conditions

Chronic Periodontitis, Generalized Chronic Disease Chronic Periodontitis Disease Attributes Mouth Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Periodontal Diseases Periodontitis Stomatognathic Diseases

Age range

40 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

About this study

The aim of the present study was to monitor the clinical outcomes and the metabolic response of non-surgical periodontal therapy in patients with chronic periodontitis and uncontrolled type 2 diabetes.

Regarding clinical and metabolic parameters at baseline, no differences were displayed between two groups. However, at 3-months follow-up period the patients within a test group were demonstrated better clinical outcomes than patients in a control group

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Diagnosis of diabetes type 2 for more than five years Type 2 diabetes with HbA1c level from 7% to 9% at the last medical evaluation Diagnosis with chronic periodontitis

Exclusion criteria

Pregnancy

Alcoholism and smoking
Presence of any systemic disorders other than hypertension and diabetes
Diabetic major complications

Treatment and study plan

amoxicillin 500mg and metronidazole 400mg

Combination Product

metronidazole 400mg and amoxicillin 500mg three times daily for two weeks

Other names: Amoxil and Flagyl

Primary outcomes

glycosylated haemoglobin (HbA1c)

Time frame: 3 months

Blood was taken from a peripheral vein to monitor HbA1c using high-performance liquid chromatography

Sponsors and collaborators

Lead sponsor

Taibah University

Other

Registry information

Official study title

The Effects of Non -Surgical Periodontal Therapy on Glycemic Control and Periodontal Health in Diabetic Patients With Periodontitis (Randomized Controlled Clinical Trial)

Important dates

Study start: 2015
Primary completion: 2016
Study completion: 2016
First posted: Dec 21, 2018
Registry last updated: Oct 21, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed