The Effects Of HMO On The Faecal Microbiota And On Gastrointestinal Symptoms In Healthy Volunteers

Inclusion criteria

• Signed written informed consent
• Ability and willingness to understand and comply to the study procedures

Exclusion criteria

• Participation in a clinical study one month prior to screening visit and throughout the study.
• Abnormal results of the screening laboratory tests clinically relevant for study participation, as judged by the investigator.
• Any gastrointestinal symptom scored >3 on the GSRS during the screening period
• A mean score on the total GSRS >2 (i.e. above the population norm value) during the screening period
• Any gastrointestinal disease(s) that may cause symptoms or may interfere with the trial outcome, as judged by the investigator.
• Other severe disease(s) such as malignancy, diabetes, severe coronary disease, kidney disease or neurological disease, as judged by the investigator.
• Severe psychiatric disease, as judged by the investigator.
• Use of highly dosed probiotic supplements (yoghurt allowed) 3 months prior to the study and throughout the study.
• Consumption of antibiotic drugs 3 months prior to screening and throughout the study.
• Consumption on a regular basis of medication that might interfere with symptom evaluation (as judged by the investigator) 2 weeks prior to screening and throughout the study.
• Pregnant or lactating or wish to become pregnant during the period of the study.
• Lack of suitability for participation in the study for any reason as judged by the investigator.