Affiliated Hospital of Zunyi Medical University
Zunyi, Guizhou, 563000, China
Location status: Recruiting
NCT Number: NCT06514729
The objective of this study was to discuss the effects of different ventilation modes on patients with plasma inflammatory factor and respiratory function in patients with pulmonary removal.
Interested in participating?
Request Info18 year–75 year
All sexes
Interventional
Not applicable
Zunyi, Guizhou, 563000, China
Location status: Recruiting
Patients who meet the inclusion criteria will be numbered in the order of admission, and a dedicated person will prepare codes and opaque envelopes for random allocation. This study was divided into 3 groups, one groups was ventilation side volume control ventilation+continuous positive pressure ventilation on the non ventilation side, the other groups was ventilation side volume control ventilation+continuous positive pressure ventilation on the non ventilation side; the other groups was ventilation side pressure regulated volume control ventilation+continuous positive pressure ventilation on the non ventilation side.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Comprehensive examination and analysis of imaging, laboratory examination and other comprehensive examinations, the diagnosis is clear, which is in line with lobe resection surgical indications
Age 18-75 years old, the gender is not limited;
ASA grading Ⅰ ~ III level;
It is expected that the single lung ventilation time is ≥1 hours, and ≤3 hours
Exclusion criteria
Emergency surgery;
There is a taboos on the existence of systemic anesthesia;
There is a history of acute chronic upper respiratory infections in the past January;
Previous bronchial asthma, chronic obstructive pulmonary disease, bronchial dilatation, phthisis ,aspergillosis , acute respiratory distress syndrome or history of respiratory failure;
Merge the function of important organs such as heart, liver, and kidney;
There was a history of chest surgery and the history of trauma;
Preoperative lung function test obvious abnormal abnormal abnormalities (1 second of exhalation (FEV1) <60%);
Patients refuse to participate in the clinical trial
The ventilation side adopts different ventilation modes combined with continuous positive pressure ventilation on the surgical side.
Time frame: Within 15 days after surgery
The clinical pulmonary infection score index is mainly used to evaluate the severity of pulmonary infection, which involves many factors, including: body temperature, white blood cell count, tracheal secretions, oxygenation, X-ray chest X-ray, and the progress of pulmonary infiltrates. The maximum score is 12 points, and the severity of infection is directly proportional to its score.
Contact information is provided by the study sponsor or research team.
Mao Enting
Other
The Effects of Different Ventilation Modes on Patients With Plasma Inflammatory Factor and Respiratory Function in Patients With Pulmonary Lobe Resection
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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