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Completed

NCT Number: NCT07228546

The Effects of Demographic and Clinical Data of Patients on Cerebral Oxygen Monitoring Values

The aim of this study is to examine the effects of patients' clinical and demographic datas on cerebral oxygen saturation values. Brain oxygenation is measured using near infrared spectroscopy (NIRS). The primary outcome measure of the study is the regional oxygen saturation (rSO2) values measured on the monitor at twelve time points. The other primary outcome measures consist of baseline arterial and venous blood gas analysis and baseline activated clotting time measurements.

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Key information

Conditions

Cerebral Oxygen Saturation

Age range

25 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Tuna Şahin

Adana, Yüreğir, 01370, Turkey (Türkiye)

About this study

This prospective observational study analyzes 80 patients between the ages of 25-80 years who are undergoing elective coronary artery bypass grafting (CABG) surgery. Demographic data of the patients such as age, gender, comorbidities, body mass index are recorded. In addition to standard monitoring, cerebral oximetry monitoring (NIRS) is applied to the patients. Baseline arterial and venous blood gas analysis values, baseline activated clotting time measurements are recorded. Durations of anesthesia, surgery , cardiopulmonary bypass , aortic cross- clamping are recorded. Time points for rSO2 values are baseline, induction, sternotomy, cannulation, pump entry, cross clamp placement, 34º C ,36º C, lowest temperature, cross clamp removal, pump exit, skin closure.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Accepting to participate in the study
  • Undergoing elective coronary artery bypass grafting surgery
  • Age 25-80 years Ejection fraction 30% and above

Exclusion criteria

  • Non volunteers
  • Age <25 or >80 years
  • Ejection fraction below 30%
  • Patients with history of neurological disease or neurosurgery
  • Emergency surgery
  • Concurrent valve surgery
  • Patients with history of carotid artery stenosis
  • Patients with need for preoperative intraaortic balloon pump or inotropic support

Treatment and study plan

Primary outcomes

  1. Regional oxygen saturation values

    Time frame: Baseline and peroperative measurements until the and of surgery

    Regional oxygen saturation values measurement at twelve points.

  2. Baseline arterial blood gas analysis

    Time frame: Within 5 minutes after arterial cannulation for the baseline measurement

    The baseline arterial blood gas sample taken from the patient after arterial cannulation

  3. Venous blood gas analysis

    Time frame: Within 5 minutes after central jugular venous cannulation

    Venous blood gas sample taken from the patient after central jugular venous cannulation

  4. Baseline activated clotting time measurement

    Time frame: Within 5 minutes after arterial cannulation for the baseline measurement

    The baseline measurement of activated clotting time after arterial cannulation

Sponsors and collaborators

Lead sponsor

Tuna Şahin

Other

Registry information

Official study title

The Effects of Demographic and Clinical Data of Patients on the Assessment of Cerebral Oxygen Monitoring Values Applied During Coronary Artery Bypass Grafting

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Nov 14, 2025
Registry last updated
Jan 7, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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