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NCT Number: NCT07075068

The Effects of Cigarette Addiction on Lower Extremity Movement Speed and Coordination

This observational study will aim to investigate the effects of cigarette addiction on lower extremity motor coordination and movement speed in young adults. The study will include healthy participants aged 18-25 years, divided into smokers and non-smokers. Motor coordination will be assessed using the Lower Extremity Motor Coordination Test (LEMOCOT), and speed will be evaluated with a 30-meter sprint test. Nicotine dependence will be evaluated in smokers using the Fagerström Test. The findings will provide insight into the possible functional impacts of nicotine addiction on motor performance.

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Key information

Age range

18 year–25 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Esra Pehlivan

Istanbul, Üsküdar, 34668, Turkey (Türkiye)

Location status: Recruiting

Location contact

ESRA PEHLİVAN

CONTACT

[email protected]

02164189616

About this study

The study will be conducted as a non-randomized controlled observational trial at the Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation. A total of 24 healthy young adults (12 smokers, 12 non-smokers) will participate. The inclusion criteria will require participants to be aged 18-25, cooperative, literate, and able to walk independently. Participants will be categorized as smokers based on WHO and DSM-IV-TR criteria. The primary assessments will include LEMOCOT and 30-meter sprint test. Nicotine addiction will be measured using the Fagerström Test for Nicotine Dependence (FTND), and anthropometric data including BMI and bimalleolar diameter will also be recorded. Data will be analyzed to determine any statistical differences or correlations between smoking status and motor performance outcomes.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

(for both groups):

  • Age between 18 and 25 years
  • Able to walk independently
  • Literate and cooperative
  • Willing to participate voluntarily
  • BMI between 18.5 and 29.9 kg/m²

Additional inclusion for smokers:

  • Daily smoking for at least one year based on WHO and DSM-IV-TR definitions
  • Exclusion Criteria (for all participants):
  • Orthopedic, neurologic, or neuromuscular disorders affecting gait
  • Chronic cardiopulmonary disease
  • Cognitive impairments
  • Obesity (BMI ≥ 30 kg/m²)

Additional exclusion for smokers:

  • History of acute cardiovascular events
  • Chronic heart failure or lung diseases

Treatment and study plan

Behavioral and Functional Performance Assessment Battery

Diagnostic Test

This study will include only observational functional assessments. No active intervention will be performed.This observational protocol will involve standardized assessments of lower extremity coordination (LEMOCOT), movement speed (30-meter sprint), and smoking-related behavioral patterns (Fagerström Test for Nicotine Dependence). These tools will be used to evaluate the potential impact of cigarette addiction on physical performance in young adults. No therapeutic or pharmacological intervention will be applied.

Primary outcomes

  1. LEMOCOT Score (Lower Extremity Motor Coordination Test)

    Time frame: Baseline

    The number of correct taps within 20 seconds will be measured for each participant.

  2. 30-Meter Sprint Time

    Time frame: Baseline

    Time (in seconds) required to complete a 30-meter sprint will be recorded and averaged from two trials.

Secondary outcomes

  1. Fagerström Test for Nicotine Dependence Score

    Time frame: Baseline

    Degree of nicotine dependence will be evaluated in smokers using the Fagerström Test for Nicotine Dependence.

  2. Body Mass Index (BMI)

    Time frame: Baseline

    BMI will be calculated using height and weight measurements (BMI = weight (kg) / height² (m²)).

  3. Bimalleolar Circumference and Diameter Measurement

    Time frame: Baseline

    The circumference at the level of the medial and lateral malleoli will be measured using a flexible tape measure while the participant is in a supine position.

Study contacts

Contact information is provided by the study sponsor or research team.

ESRA PEHLİVAN

CONTACT

[email protected]

+90 777 87 77

Edanur Kocakaplan

CONTACT

[email protected]

Sponsors and collaborators

Lead sponsor

Saglik Bilimleri Universitesi

Other

Registry information

Official study title

The Effects of Cigarette Addiction on Lower Extremity Movement Speed and Coordination in Young Adults

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jul 20, 2025
Registry last updated
Jul 30, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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