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OpenTrials
Completed

NCT Number: NCT00909064

The Effects of Arixtra on Wound Drainage Following Total Joint Arthroplasty

The investigators hypothesize that Arixtra patients will be less likely to experience wound infection than patients who have received low-molecular weight heparin, coumadin or aspirin with mechanical compression.

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Key information

Conditions

Total Knee Replacement

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

U C Davis

Sacramento, California, 95817, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All primary unilateral TKA and THA cases will be included.

Exclusion criteria

  • Patients less than 50 kg, Patients with CrCl<30ml/min. Revision and bilateral procedures will be excluded.

Treatment and study plan

Fondaparinux Sodium (Arixtra)

Drug

2.5 mg once per day to begin 6-8 hours after surgery and continued for 10 days.

Other names: Arixtra

Primary outcomes

  1. Number of Days Until a Dry Wound

    Time frame: Up to 10 days

    Days from day of surgery to stoppage of leakage from the wound

Secondary outcomes

  1. Number of Days in Hospital.

    Time frame: Up to 10 days

    Days after surgery to dischage

  2. Incidence of Wound Infection

    Time frame: Up to 10 days

    Incidence of Cellulitis in patients undergoing Arixtra treatment

Sponsors and collaborators

Lead sponsor

Paul Di Cesare,MD

Other

Registry information

Important dates

Study start
2009
Primary completion
2009
Study completion
2009
First posted
May 27, 2009
Registry last updated
May 15, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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