Clinical Trial Center for Functional Foods; Chonbuk National University Hospital
Jeonju, Jeollabuk-do, 561-712, South Korea
NCT Number: NCT02138851
The investigators performed a 8-week, randomized, double-blind, placebo-controlled human trial to evaluate the efficacy and safety of Fig paste on functional constipation. The investigators measured colon transit time, frequency of defecation, defecation time, stool type, and abdominal discomfort.
Looking for future studies?
Notify Me19 year–39 year
All sexes
Interventional
Phase 2 / Phase 3
Jeonju, Jeollabuk-do, 561-712, South Korea
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Ficus Carica (300g/day), parallel design
Placebo (300g/day), parallel design
Time frame: 8 weeks
Colon transit time was measured in study baseline and visit 3(8 week). Colonic transit time was measured by the method of Metcalf et al,. Subjects ingested a once-daily series of three distinctive ColomarkTM capsules at the same time each day for three consecutive days. Each capsule contained twenty radioopaque makers of a ring shape. Subjects then received abdominal X-rays 24 after the ingestion of the final capsule. Abdominal X-rays through a Number of markers present was confirmed. The CTT was calculated as the sum of the markers detected on X-ray.
Time frame: 8 week
Frequency of defecationI was measured in study baseline and visit 3(8 week).
Time frame: 8 week
Defecation time was measured in study baseline and visit 3(8 week).
Time frame: 8 week
Stool type was measured in study baseline and visit 3(8 week). Stool type is composed as follows: Separate hard lumps, like nuts. (score 1); Sausage-shaped but lumpy (score 2); Like a sausage or snake but with cracks on its surface (score 3); Like a sausage or snake, smooth and soft. (score 4); Soft blobs with clear-cut edges (score 5); Fluffy pieces with ragged edges, a mushy stool (score 6); Watery, no solid pieces (score 7). The average score is closer to the three-point mode means a normal stool.
Time frame: 8 week
Abdominal discomfort was measured in study baseline and visit 3(8 week). Abdominal discomfort each question is composed as follows: Very poor (score 1); Poor (score 2); Average (score 3); Good (score 4); Very good (score 5). A higher score means severe abdominal pain.
Chonbuk National University Hospital
Other
Randomized, Double-Blind, Placebo-Controlled, Parallel Trial in Subjects With Functional Constipation, to Evaluate the Improvement in Constipation of Ficus Carica
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT06196073
Functional Constipation
Denizli, Pamukkale, Turkey (Türkiye)
View Trial DetailsNCT06730594
Functional Constipation
Vadodara, Gujarat, India
View Trial DetailsNCT04166058
Functional Constipation, Irritable Bowel Syndrome With Constipation
Birmingham, Alabama, United States
View Trial DetailsNCT05760313
Functional Constipation
Phoenix, Arizona, United States
View Trial Details