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Completed

NCT Number: NCT06809855

The Effectiveness of Using a Single Post-operative Intramuscular Dexamethasone Injection on Patients with Surgical Extraction of Lower Third Molar

Evaluating the effectiveness of using a single immediate postoperative intramuscular Dexamethasone injection on pain, swelling, trismus and tissue healing in the first seven days.

Methods: A split mouth technique on 16 patients with bilateral similar impacted mandibular third molar were extracted; one side was given 8mg intramuscular injection of dexamethasone (study group) and the other side wasn't given injection (control group) and compare of the two sides were done in the following seven days.

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Key information

Conditions

Dexamethasone Administration Post Extraction Complication

Age range

15 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1

Primary location

Department of Oral and Maxillofacial Surgery, College of Dentistry, University of Baghdad

Baghdad, Iraq

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • bilateral similar impacted lower third molar
  • willing to do surgical extraction

Exclusion criteria

  • Patients who are not fulfill the inclusion criteria
  • allergic to dexamethasone
  • who has medical diseases
  • taking any medications
  • pregnant or lactating women

Treatment and study plan

Dexamethasone

Drug

single 8mg post-operative intramuscular injection

Primary outcomes

  1. post operative pain changes

    Time frame: each participant was seen at 1st, 3rd and 7th post-operative days

    measurement of change in pain on visual scale analog from 10 to 1 , 10 mean the worst pain and 1 is least pain

  2. Change in post operative swelling

    Time frame: each participant was seen at 1st, 3rd and 7th post-operative days

    The swelling was measured between two points marked on skin in millimeters using ruler

  3. Post operative Change in mouth opening

    Time frame: each participant was seen at 1st, 3rd and 7th post-operative days

    The distance between upper and lower incisors was measured in millimeters using ruler

Secondary outcomes

  1. Tissue healing

    Time frame: Healing was assessed on the 7th postoperative day

    Healing of extraction site was assessed by using Landry, Turnbull and Howley index

Sponsors and collaborators

Lead sponsor

Yassir R. Al-khannaq

Other

Registry information

Official study title

The Effectiveness of Using a Single Post-operative Intramuscular Dexamethasone Injection on Patients with Surgical Extraction of Lower Third Molar(Split Mouth Technique)

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Feb 5, 2025
Registry last updated
Feb 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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