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NCT Number: NCT07396948

The Effectiveness of Two Physiotherapy Protocols in the Treatment of Patellofemoral Pain Syndrome

Patellofemoral pain syndrome (PFPS) is one of the most common causes of anterior knee pain in young and active individuals. PFPS is characterized by anterior knee pain. The treatment of choice is conservative management. However, there is still lack of widely accepted physiotherapeutic strategies aimed at alleviating patellofemoral pain. The outcomes of conservative treatment remain unsatisfactory. Therefore, the aim of this study was to compare the effectiveness of two physiotherapy protocols based on manual therapy and muscle training in the treatment of patellofemoral pain

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Key information

Age range

18 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

anterior knee pain (unilateral or bilateral) lasting at least one month -

Exclusion criteria

previous knee injuries or surgeries, systemic diseases, patellar dislocation or subluxation, patellar maltracking, ligamentous laxity, patellar tendon pathologies, spinal pain, other abnormalities such as leg length discrepancy >2 cm, patients treated pharmacologically, with physiotherapy, or acupuncture in the knee area within the past 30 days

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Treatment and study plan

medial patellar mobilization

Other

Patellar mobilization was carried out three times for 60 seconds each session [19]. The technique was performed by placing the therapist's thumbs on the lateral edge of the patella allowing a patellar glide in the medial and slightly caudal direction. The aim of this technique was to stretch the lateral patellar retinaculum

quadriceps muscle stretching

Other

In order to perform this technique the patient was positioned prone on a treatment table (Figure 6). The non-stretched limb remained on the ground, flexed at the hip and knee. Moving this limb forward ensured proper aligment of the lumbar spine, while elevating the heel and placing it on the therapist's foot reduced tension in the hamstring group. Proper execution of the technique could be performed when the pelvis was aligned parallel to the surface, keeping the trunk and thigh of the stretched limb in one line. The therapist grasped by ipsilateral hand the distal third of the patient's lower leg and pulled the heel toward the buttock while by the contralateral hand stabilized the pelvis. The static position of stretching was maintained for 30 seconds in every repetition.

Training Protocol

Other

The training protocol included the following exercise:

glute bridges, half squat, rear lunges, side walk with elastic band

Primary outcomes

  1. AKPS score

    Time frame: 6 weeks

  2. VAS scale

    Time frame: 6 weeks

Study contacts

Contact information is provided by the study sponsor or research team.

Piotr Łuczkiewicz, prof.

CONTACT

[email protected]

600 905 075

Sponsors and collaborators

Lead sponsor

Medical University of Gdansk

Other

Registry information

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Feb 9, 2026
Registry last updated
Feb 9, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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