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OpenTrials
Completed

NCT Number: NCT05424952

The Effectiveness of Conversational AI Service (Chatbot) Utilization on Vaccine Confidence

The primary objective of this study is to develop and evaluate a conversational AI service (chatbot) on social media platforms to obtain accurate and up-to-date vaccine information, and assess the impact of chatbot usage on users' vaccine confidence and acceptance in Hong Kong, Singapore, and Thailand.

Completed

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Key information

Conditions

Vaccination Hesitancy Behavior Health Behavior Treatment Adherence and Compliance Treatment Refusal Vaccination Refusal

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

The University of Hong Kong, Hong Kong

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About this study

The investigators will focus on vulnerable seniors and/or children from Hong Kong, Singapore and Thailand who have refused or delayed COVID-19 vaccination. Participants will be recruited by an online panel to meet the target quota by age and sex. Participants will then be randomly assigned to the intervention group and the control group. For both intervention and control groups, evaluation questionnaires will be given out to the study participants asking questions about their demographics, including age, sex, educational level, employment status and household income levels. Participants will then answer questions regarding COVID-19 vaccine confidence, including the effectiveness and safety of vaccines, and the motivations of the policymakers who decided on the needed vaccines. Participants will be asked about COVID-19 vaccine acceptance including the intention to receive COVID-19 vaccines, make plans to receive COVID-19 vaccines, and receive at least one dose of COVID-19 vaccines. The intervention group will then be asked to use the chatbot developed by the research team for up to two weeks. The chatbot is developed under the RE-AIM framework for formative, impact, and process evaluation of the intervention. The control group will have no exposure to the chatbot.

The chatbot will be supported with data from 1) social listening analytics for monitoring local real-time discourses in the digital space on COVID-19 vaccine hesitancy and misinformation, and 2) formative, baseline, and endpoint evaluation, which will generate evidence for development and improvement/refinement.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Hong Kong adult residents (English or Chinese users) with (a) unvaccinated senior parents/grandparents aged 60 (including those who received first dose after the announcement of the COVID passport on 4th of January) or (b) unvaccinated children aged below 18.
  • Thailand adult residents (Thai users) with (a) unvaccinated senior parents/grandparents aged 60 or above or (b) unvaccinated children aged below 18.
  • Singapore adult residents (English or Chinese users) with unvaccinated children aged between 5 to 11 years old.

Exclusion criteria

  • People who do not meet the inclusion criteria.

Treatment and study plan

Conversational AI Service (Chatbot)

Other

WhatsApp or Messenger Chatbot for COVID-19 vaccines

Primary outcomes

  1. Covid-19 vaccines confidence Index

    Time frame: 1 week

    • "Overall, I think COVID-19 vaccines are important for children/senior parents (or grandparents)"
    • "Overall, I think COVID-19 vaccines are safe for children/parents (or grandparents)"
    • "Overall, I think COVID-19 vaccines are effective for children/parents (or grandparents)"

    The response is a 5-point Likert scale: (a) Strongly agree (b)Tend to agree (c) Do not know (d) Tend to disagree (e) Strongly disagree

  2. Covid-19 vaccines acceptance

    Time frame: 1 week

    • What is the vaccination status of your children/senior parents (or grandparents) as of now?
    • Is vaccinated with at least the first dose of the vaccine
    • Has made an appointment but has not been vaccinated with the first dose yet
    • Has not made an appointment but will get the vaccine.
    • Has no plan to get vaccinated anytime soon.
    • Do you want your children/senior parents (or grandparents) vaccinated against COVID-19 if vaccination is indicated and available for them?
    • Yes, definitely.
    • Unsure, but leaning towards yes.
    • Unsure, but leaning towards no.
    • No, definitely not.

Sponsors and collaborators

Lead sponsor

The University of Hong Kong

Other

Collaborators

  • Health Intervention and Technology Assessment Program (HITAP)
  • National University of Singapore

Registry information

Important dates

Study start
2022
Primary completion
2023
Study completion
2023
First posted
Jun 21, 2022
Registry last updated
Dec 6, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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