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NCT Number: NCT07654270

The Effect of Water Temperature on Heart Rate Variability and Cognition

Heart rate variability (HRV) is a key indicator of fitness, and stress resilience. Previous research has shown that HRV decreases under mental workload, including during tasks that require strict attention. Studies also show that temperature exposure affects attention: cold increases the stress response while warm water has a calming effect. Very few studies combine thermal exposure with cognitive testing, and no controlled trials have investigated whether water temperature modulates HRV responses specifically during cognitive demand.

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Key information

Conditions

Age range

18 year–30 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

About this study

Heart rate variability (HRV) is a widely recognized physiological marker that reflects the dynamic interaction between the cardiovascular and autonomic nervous systems. HRV represents millisecond-level fluctuations in time between consecutive heartbeats. It is a key indicator of autonomic nervous system balance, with higher values indicate better recovery, fitness, and stress resilience. Previous research has shown that HRV decreases under mental workload, including during tasks that require attention, inhibition, or executive function.1-3 Studies also show that temperature exposure affects autonomic regulation: cold increases sympathetic drive, while warm water supports parasympathetic activation.4-6 Very few studies combine thermal exposure with cognitive testing, and no controlled trials have investigated whether water temperature modulates HRV responses specifically during cognitive demand.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy women free of chronic disease (by self-report)
  • 18-30 years of age

Exclusion criteria

  • medication/drug use that has not been consistent for the previous 3 months or will be discontinued during the trial
  • any acute illness
  • regular use of cigarettes or marijuana
  • pregnant or lactating women
  • not fluent in English
  • not willing to attend two in-person lab visits in downtown Phoenix and follow study protocol (including abstaining from caffeine in the 12 hours prior to testing)
  • not currently competing in sports or unusually high-intensity exercise protocols (e.g., high-intensity exercise greater than 30 minutes most days of the week)

Treatment and study plan

Water

Other

water temperature

Primary outcomes

  1. heart rate variability

    Time frame: 3 minutes

    the measure of the variation in time between consecutive heartbeats

  2. cognitive performance

    Time frame: 3 minutes

    Trail making test that measures cognitive flexibility, visual attention, and executive function, with interpretation based on completion times (in seconds)

Secondary outcomes

  1. cognitive performance

    Time frame: 3 minutes

    Stroop Color-Word Test which measures attention span, reaction time, and ability to resist distractions

  2. cognitive performance

    Time frame: 3 minutes

    reaction time: measured by the elapsed time between stimulus onset and an individual's response

Study contacts

Contact information is provided by the study sponsor or research team.

Carol Johnston

CONTACT

[email protected]

6024963463

Sponsors and collaborators

Lead sponsor

Arizona State University

Other

Registry information

Official study title

Effects of Water Temperature on Heart Rate Variability During Cognitive Testing in Healthy Adult Women: A Randomized Crossover Trial

Important dates

Study start
2026
Primary completion
2026
Study completion
2027
First posted
Jun 17, 2026
Registry last updated
Jun 17, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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