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OpenTrials
Completed

NCT Number: NCT02878265

The Effect of Vitamin A With and Without Zinc and Multivitamin Supplementation on Malaria Morbidity in Ghanaian Children

The aim of this study was to determine the effect of combining vitamin A (VA), zinc (Z) and multivitamins (MV- A, B1, B2, B6, B12, C, D and E) on malaria morbidity

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Key information

Conditions

Malaria Infections Mosquito-Borne Diseases Parasitic Diseases Protozoan Infections Vector Borne Diseases

Sex eligibility

Female

Study type

Interventional

Phase

Phase 3

Primary location

Amoako

Accra, 233, Ghana

About this study

A total of 542 children aged between 6-59 months received either: (i) VA (control) or (ii) VA & Z (VAZ) or (iii) VA, Z & MV (VAZM). VA was delivered as a single dose while MV and Z were delivered daily. Malaria cases were managed by community health workers, who used rapid diagnostic test to confirm infection prior to treatment.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • under 5years
  • will stay in the community for 10years

Exclusion criteria

  • chronic diseases

Treatment and study plan

Vitamin A

Dietary Supplement

Vitamin A supplements

Other names: VA

vitamin A and zinc

Dietary Supplement

Combination of vitamin A and zinc supplements

Other names: VAZ

Vitamin A , Zinc and Multivitamin

Dietary Supplement

Combination of vitamin A, zinc and multivitamins

Other names: VAZM

Primary outcomes

  1. Incidence of clinical malaria attacks

    Time frame: Baseline and every month up to six months

    While taking the supplement, malaria incidence will be measured

Secondary outcomes

  1. Incidence of diarrhea attacks

    Time frame: Every month up to six months

    While taking the supplement, diarrhea incidence will be measured

Sponsors and collaborators

Lead sponsor

University of Ghana

Other

Collaborators

  • Kwame Nkrumah University of Science and Technology

Registry information

Important dates

Study start
2011
Primary completion
2012
Study completion
2012
First posted
Aug 25, 2016
Registry last updated
Aug 25, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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