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OpenTrials
Completed

NCT Number: NCT01085006

The Effect of Tranexamic Acid on Postpartum Hemorrhage During and After Cesarean Delivery

Intravenous Tranexamic acid is used to reduce the hemorrhage during and after cesarean delivery in a double blind randomized placebo controlled trial.

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Key information

Conditions

Hemorrhage Pathologic Processes Pathological Conditions, Signs and Symptoms

Sex eligibility

Female

Study type

Interventional

Phase

Phase 1 / Phase 2

Primary location

Laleh Eslamian

Tehran, 14114, Iran

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Term pregnancy
  • Single fetus
  • Maximally only one previous cesarean delivery

Exclusion criteria

  • More than one previous cesarean delivery
  • Hx of other abdominal or pelvic surgery
  • Hx of medical disorders
  • Hx of thromboembolic disorders
  • Polyhydramnios
  • Macrosomia
  • Preeclampsia
  • Hx of sensitivity to Tranexamic acid
  • Abnormal Pt, PTT, PT or INR

Treatment and study plan

Tranexamic Acid

Drug

Tranexamic acid in cases, normal saline in controls

normal saline

Drug

Tranexamic acid in cases, normal saline in controls

Primary outcomes

  1. The Amount of Hemorrhage During Cesarean Delivery and Within 2 Hours Afterward

    Time frame: During the procedure and within 2 hours afterwards

Secondary outcomes

  1. Amount of Hemorrhage in the First 24 Hour After Cesarean Delivery

    Time frame: First 24 hours

Sponsors and collaborators

Lead sponsor

Tehran University of Medical Sciences

Other

Registry information

Official study title

The Effect of Tranexamic Acid Administration on Postpartum Hemorrhage During and After Cesarean Delivery

Important dates

Study start
2009
Primary completion
2010
Study completion
2010
First posted
Mar 11, 2010
Registry last updated
Jan 25, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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