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Completed

NCT Number: NCT01123993

The Effect of Thai Traditional Music on Cognitive Function, Psychological Health and Quality of Sleep Among Thai Older Individuals With Dementia

To determine the effect of Thai traditional music on cognitive function, psychological health and quality of sleep among Thai older individuals with dementia.

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Key information

Age range

60 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Primary location

Neurologic Clinic, Division of Neurology, Department of Medicine, Phramongkutklao Hospital, Bangkok, Thailand

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About this study

Dementia, regardless of its cause, has been recognized to be one of the most important and common problems among the elderly worldwide. The prevalence of dementia has been increasing gradually throughout the world. It is associated with medical and psychological consequences, especially in the advanced stage of the condition. Medications for dementia, specifically, acetylcholine esterase inhibitors, have proven efficacy but variable individual response. They are very expensive and stress families and insurance payers. Dementia and its neuropsychiatric co-morbidities effects not only individual patients, but also family members and care givers as it stresses interpersonal relationships, increases the need for personal care, nursing home placement, and the use of neuropsychiatric medications. Any new approach to improve cognitive function, behavior, mood and sleep quality among demented individuals therefore could have far reaching benefits for patients, care givers, financially responsive parties, and the country as a whole.

There are several studies focusing on the non-pharmacologic approaches to care of the demented. The objectives were to reduce reliance on prescribed medications with these adjunctive therapies. One of the interesting non-drug trials was about music therapy. It was found that music could improve behavioral and social functions among individual demented patients. However, the methodology of each music study varied considerably. To our knowledge, there has been no music study in dementia performed in Thailand using our unique Thai traditional music. We therefore aim to study this non-pharmacologic approach in Thai demented individuals using Thai traditional music. We hypothesized that regular listening to Thai traditional music will improve cognitive function, activities of daily living, mood, behavior and sleep quality in Thai demented patients.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age > 60 years
  • Diagnosed with Alzheimer's disease, vascular dementia or mixed dementia by ICD-10
  • No change in neuropsychiatric drugs for at least 4-week before and 8-week during the study
  • CD player available at home
  • Patient and care giver consent to study

Exclusion criteria

  • Severe depression requiring aggressive treatment or hospitalization
  • Dementia with Lewy body, multisystem atrophy
  • Treatable dementia
  • Active medical problems
  • Profound hearing loss

Treatment and study plan

Music CD

Device

During 4-week interventional period of each group, a researcher gives a CD to care giver and advises him/her to open the music for patient for at least 60 minutes daily, after dinner to bedtime. Meanwhile, the care giver notes the exact duration that patient actually listens to it in the calendar provided and returns the CD and document to the researcher at the end of interventional period.

Primary outcomes

  1. Depression

    Time frame: 4-week after regularly listening to the music for 28 days

    Using Thai Geriatric Depression Scale (TGDS)

  2. Activities of Daily Living

    Time frame: 4-week after music

    using AD Cooperative Study Activities of Daily Living Inventory (ADCS/ADL)

  3. Behavior

    Time frame: 4-week after music

    Using Behavioral pathology in Alzheimer's Disease Rating Scale (BEHAVE AD)

  4. Sleep quality

    Time frame: 4-week after music

    Using Pittsburgh Sleep Quality Index (PSQI)

Secondary outcomes

  1. reduction of the care giver's stress and burden

    Time frame: 4-week after intervention

    Using visual analog scale

Sponsors and collaborators

Lead sponsor

Phramongkutklao College of Medicine and Hospital

Other

Registry information

Official study title

The Effect of Thai Traditional Music on Cognitive Function, Psychological Health and Quality of Sleep Among Thai Older Individuals With Dementia.

Important dates

Study start
2010
Primary completion
2010
Study completion
2010
First posted
May 14, 2010
Registry last updated
Jan 5, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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