Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT06869304

The Effect of Steep Trendelenburg Position on Neurocognitive Functions in Robotic Radical Prostatectomy Cases

The aim of this study is to evaluate the effects of the steep Trendelenburg position in robotic prostatectomy cases, where anesthesia depth is monitored using BIS and cerebral perfusion is tracked with NIRS, and to determine the incidence of neurocognitive dysfunction using the MoCA test in the postoperative period.

Steep Trendelenburg position and CO₂ pneumoperitoneum during robotic radical prostatectomy lead to significant changes in intracranial pressure and cerebral oxygenation, which may contribute to postoperative neurocognitive dysfunction (POCD). Monitoring anesthesia depth with Bispectral Index (BIS) and cerebral perfusion with Near-Infrared Spectroscopy (NIRS) may help detect early neurocognitive changes, and MoCA test assessments will reveal a measurable decline in cognitive function postoperatively.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Age range

65 year–100 year

Sex eligibility

Male

Study type

Observational

Primary location

Ankara City Hospital Bilkent

Ankara, Turkey (Türkiye)

Location contact

Özlem Balkız Soyal, md

SUB_INVESTIGATOR

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥ 65 years
  • ASA II-III risk score
  • Patients scheduled for robotic radical prostatectomy
  • Patients who voluntarily agree to participate

Exclusion criteria

  • Age < 65 years
  • History of neurological or psychiatric disorders
  • Inability to undergo robotic surgery
  • Conversion to open prostatectomy during surgery
  • Patients who do not consent to participate

Treatment and study plan

Montreal Cognitive Assessment

Diagnostic Test

Preoperative and postoperative MoCA test scores

Primary outcomes

  1. MoCA

    Time frame: preoperatively

    Preoperative MoCA test scores

  2. MoCA

    Time frame: day 1

    postoperative MoCA test scores

Secondary outcomes

  1. NIRS

    Time frame: intraoperatively

    NIRS values (right & left)

Study contacts

Contact information is provided by the study sponsor or research team.

Betül Güven Aytaç, Assoc.prof.

CONTACT

[email protected]

+905073578351

Sponsors and collaborators

Lead sponsor

Ankara City Hospital Bilkent

Other

Registry information

Official study title

Examining the Effect of Steep Trendelenburg Position on Neurocognitive Functions With MoCA Test in Robotic-assisted Radical Prostatectomy Surgeries.

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Mar 11, 2025
Registry last updated
Mar 11, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.