The Effect of Single Lung Ventilation Duration on Postoperative Pulmonary Complications in Thoracic Surgery

This observational study investigates the relationship between the duration of single-lung ventilation (SLV) and the incidence of postoperative pulmonary complications (PPCs) such as pneumonia, pneumothorax, hemothorax, acute lung injury, and acute respiratory distress syndrome (ARDS) in adult patients undergoing thoracic surgery. A total of 134 patients aged 18-85 years, scheduled for thoracic surgery requiring SLV, will be monitored. Data including SLV duration, perioperative parameters, and postoperative pulmonary outcomes will be analyzed.

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Key information

Conditions

Postoperative Pulmonary Complications ARDS Acute Lung Injury Lung Diseases Lung Injury One Lung Ventilation Postoperative Pulmonary Atelectasis Pulmonary Atelectasis Respiratory Tract Diseases

Age range

18 year–85 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Hazal Ekin GÜRAN AYTUĞ

Ankara, 06810, Turkey (Türkiye)

Location status: Recruiting

Location contact

Hazal EG AYTUĞ

CONTACT

[email protected]

05078448449

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age ≥18 years Undergoing thoracic surgery OLV planned during the procedure

Exclusion criteria

Pediatric patients Patients not requiring OLV Previous thoracic surgery

Treatment and study plan

One-Lung ventilation

Procedure

In this observational study, the naturally occurring duration of intraoperative single-lung ventilation (SLV) during thoracic surgery will be recorded. No intervention is applied or modified for research purposes. The exposure of interest is the total duration (in minutes) of SLV, which will be timed from initiation to termination during surgery. This variable will be analyzed in relation to postoperative pulmonary complications.

Primary outcomes

Postopertive Pulmonary Complications

Time frame: postoperative 7 days

Postoperative pulmonary complications (PPCs) are defined as respiratory events occurring within the first seven days following thoracic surgery, which negatively impact patient outcomes. In this study, PPCs include pneumonia, pneumothorax, hemothorax, acute lung injury, acute respiratory distress syndrome (ARDS), prolonged oxygen requirement, unplanned reintubation, and the need for non-invasive ventilation. These complications will be identified through clinical assessment, arterial blood gas analysis, and postoperative imaging such as chest X-rays. Each case will be evaluated using predefined diagnostic criteria to ensure consistency. The incidence of PPCs will be analyzed in relation to the duration of intraoperative single-lung ventilation.

Study contacts

Contact information is provided by the study sponsor or research team.

Hazal EG AYTUĞ

CONTACT

[email protected]

05078448449

Sponsors and collaborators

Lead sponsor

Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

Other

Registry information

Official study title

Does Duration Matter? A Study on Single-Lung Ventilation Time and Pulmonary Complications in Thoracic Procedures

Important dates

Study start: 2025
Primary completion: 2025
Study completion: 2026
First posted: Aug 3, 2025
Registry last updated: Dec 18, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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