NCT Number: NCT02858596
The Effect of Semi-solid Feeding After Percutaneous Endoscopic Gastrostomy (PEG) on the Incidence of Aspiration Pneumonia and Postoperative Length of Stay
Percutaneous endoscopic gastrostomy (PEG) is a minimally invasive procedure for long-term enteral tube feeding in patients with insufficient oral intake. Although peristomal site infection is often noted as the most common adverse event after PEG tube placements, it is seldom life-threatening and considered a minor adverse event. Feeding-related adverse events have been identified as the main cause of death after PEG, with up to 50% of postoperative early mortality (30 days) being attributed to aspiration pneumonia. This may be related to the persistence of gastroesophageal reflux (GER) of enteral feed after gastrostomy, even though PEG have been demonstrated to be superior to nasogastric tube feeding in terms of preventing GER. It has been more than a decade since semi-solid feeds were developed as an alternative to conventional liquid feeds to prevent feeding-related adverse events. Unfortunately, there is limited published literature on this topic despite the wide usage of this feeding method in Japan. Amidst the growing popularity of this method and the introduction of National Healthcare Insurance coverage for semi-solid feed prescriptions, we initiated a semi-solid feed protocol along with our existing post-PEG feeding protocols in 2014.
Looking for future studies?
Notify MeKey information
Conditions
Sex eligibility
All sexes
Study type
Interventional
Phase
Not applicable
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- Patients receiving gastrostomy tube placement in our hospital for enteral nutrition.
Exclusion criteria
- Patients receiving gastrostomy tube placement for decompression
- Patients with no gut usage more than 2 weeks before procedure
Treatment and study plan
Liquid feed (Meibalance)
Dietary SupplementPrimary outcomes
-
Incidence of aspiration pneumonia
Time frame: through study completion, average 90 days postoperation
Secondary outcomes
-
Postoperative length of stay
Time frame: through study completion, average 90 days postoperation
Sponsors and collaborators
Lead sponsor
Hiroshima Kyoritsu Hospital
Other
Registry information
Official study title
The Effect of Semi-solid Feeding After Percutaneous Endoscopic Gastrostomy (PEG) on Clinical Outcomes, Specifically the Incidence of Aspiration Pneumonia and Postoperative Length of Stay
Important dates
- Study start
- 2014
- Primary completion
- 2015
- Study completion
- 2015
- First posted
- Aug 8, 2016
- Registry last updated
- Aug 8, 2016
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Related clinical trials
Published trials that share one or more normalized conditions with this study.
Nutritional Status After Sleeve Gastrectomy in Morbid Obesity: 6-Month Study
NCT06368232
Bariatric Surgery Candidate, Body Weight
Ankara, Turkey (Türkiye)
View Trial DetailsTube Feeding in Children Having a Bone Marrow Transplant
NCT04804631
Bone Marrow Disease, Bone Marrow Diseases
London, United Kingdom
View Trial DetailsGoalKeeper: Intelligent Information Sharing for Children With Medical Complexity
NCT03620071
Brain Damage, Chronic, Brain Diseases
Palo Alto, California, United States
View Trial DetailsEffect Of High-Intensity Focused Ultrasound On Abdominal Skin Laxity Post Sleeve Gastrectomy
NCT05994079
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Connective Tissue Diseases
Dokki, Egypt
View Trial Details