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NCT Number: NCT07577973

The Effect of Self-Acupressure on Blood Pressure, Stress, and Well-Being Levels in Individuals With Hypertension

This randomized controlled trial examines the effects of nurse-led self-acupressure at HT7, LI4, PC6, and EX3 points on blood pressure, stress, and well-being in adults with primary hypertension. Participants are randomized to real acupressure, sham acupressure, or usual care groups for 2 weeks.

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Key information

Conditions

Primary Hypertension Cardiovascular Diseases Essential Hypertension Hypertension Vascular Diseases

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Aged 18-65 years
  • Diagnosed with primary hypertension (Stage 1 or 2)
  • Systolic blood pressure 130-179 mmHg or diastolic 80-109 mmHg
  • Taking antihypertensive medication
  • Able to understand and communicate in Turkish
  • Willing to provide written informed consent

Exclusion criteria

  • Secondary hypertension
  • Pregnancy or lactation
  • Severe cardiovascular disease (heart failure, myocardial infarction within 6 months)
  • Stroke history within 6 months
  • Skin lesions or infection at acupressure sites (HT7, LI4, PC6, EX3)
  • Peripheral neuropathy affecting sensation
  • Current use of anticoagulant therapy
  • Participation in another clinical trial within 30 days

Treatment and study plan

Real Acupressure

Behavioral

Acupressure applied to HT7 (Shenmen), LI4 (Hegu), PC6 (Neiguan) bilaterally, and EX3 (Yintang). Pressure applied for 15 seconds per point, 3 days per week for 2 weeks by trained researcher. Total session duration approximately 1 minute.

Sham acupressure

Behavioral

light pressure applied to non-acupoint sites 1-1.5 cm from HT7İLI4,PC6 and EX3 points for 15 seconds per site,3 days per week for 2 weeks

Usual Care

Other

Standard hypertension management including prescribed antihypertensive medication and routine clinical nursing follow-up for 2 weeks. No acupressure applied.

Primary outcomes

  1. change in blood pressure

    Time frame: baseline and week 2

    change from baseline in systolic and diastolic blood pressure measured using an automated office blood pressure monitor at 2 weeks

Secondary outcomes

  1. change in perceived stress

    Time frame: baseline, week 2

    Change from baseline in Perceived Stress Scale-14 (PSS-14) total score at 2 weeks. Scores range from 0 to 56, with higher scores indicating greater perceived stress

  2. change in mental well-being

    Time frame: baseline, week 2

    Change from baseline in Warwick-Edinburgh Mental Well-being Scale (WEMWBS) total score at 2 weeks. Scores range from 14 to 70, with higher scores indicating better mental well-being

Study contacts

Contact information is provided by the study sponsor or research team.

Seymanur Ozdemir Arslan, MSc,Phd Candidate

CONTACT

[email protected]

+90 0380 523 7827

Sponsors and collaborators

Lead sponsor

Abant Izzet Baysal University

Other

Registry information

Official study title

The Effect of Self-Acupressure on Blood Pressure, Stress, and Well-Being Levels in Individuals With Hypertension: A Three-Arm Randomized Controlled Trial

Acronym: SAPH

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
May 11, 2026
Registry last updated
May 14, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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