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OpenTrials
Completed

NCT Number: NCT03268200

The Effect of Segmental Re-examination of Colon for Adenoma Detection in Colonoscopy

The aim of this study was to determine whether segmental re-examination of the each segment (right colon, mid-colon, and left colon) could increase the proximal adenoma detection rate (ADR) and to evaluate the time-effectiveness of this approach.

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Key information

Age range

45 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Incheon St. Mary's hospital, Catholic university of Korea

Incheon, 403-720, South Korea

About this study

The investigators prospectively recruited patients (aged ≥45 and ≤75 years) who were scheduled to undergo colonoscopy at our center. Patients were excluded if they had advanced colonic cancer, prior resection of the proximal colon, inflammatory bowel disease, or polyposis syndrome, or were unable to provide informed consent. In addition, if the quality of bowel preparation was unsatisfactory (Boston Bowel Preparation Scale [BBPS] score <2 in any segment of the colon), or if the cecum could not be intubated during the colonoscopy, patients were excluded.

A randomization list was generated with the randomization algorithm of random sorting, using Excel program. Included patients were randomly assigned to one of the two groups: segmental re-examination group, in which the each segment (right colon, mid-colon, and left colon) was examined twice segmentally; or control group, in which the withdrawal time in the each segment was about 2 minutes.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients (aged ≥45 and ≤75 years) who were scheduled to un- dergo colonoscopy

Exclusion criteria

  • Patients who had advanced colonic cancer, prior resection of the proximal colon, inflammatory bowel disease, or polyposis syndrome, or were unable to provide informed consent.
  • If the quality of bowel preparation was unsatisfactory (Boston Bowel Preparation Scale [BBPS] score <2 in any segment of the colon), or if the cecum could not be intubated during the colonoscopy, patients were excluded.

Treatment and study plan

segmental reexamination

Other

segmental reexamination during colonoscopy

Primary outcomes

  1. Adenoma detection rate

    Time frame: 7 days

Secondary outcomes

  1. Per-patient adenoma detection rate (ADR) at each segment of colon

    Time frame: 7 days

  2. per-patient polyp detection rate

    Time frame: 7 days

  3. Withdrawal time

    Time frame: 1 days

Sponsors and collaborators

Lead sponsor

The Catholic University of Korea

Other

Registry information

Official study title

The Effect of Segmental Re-examination of Colon for Adenoma Detection in Colonoscopy: a Randomized, Controlled Trial

Important dates

Study start
2017
Primary completion
2019
Study completion
2019
First posted
Aug 31, 2017
Registry last updated
Jul 27, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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