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OpenTrials
Completed

NCT Number: NCT00646646

The Effect of Sedation on Eye Movements

The purpose of this study is to determine whether sedation affects saccadic eye movements.

Completed

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Key information

Conditions

Saccadic Eye Movements

Age range

19 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

General Clinical Research Center

Birmingham, Alabama, 35294, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy, human volunteers, age 19-65.
  • American Society of Anesthesiology (ASA) class I-II for inclusion criteria

Exclusion criteria

  • Pregnancy
  • Respiratory disease (severe asthma, emphysema)
  • Cardiac disease (coronary artery disease, congestive heart failure)
  • Symptomatic reflux disease
  • Advanced rheumatic disease involving cervical spine
  • Propofol or egg allergy
  • Neurological disease (stroke, intracranial processes)
  • Severe anemia

Treatment and study plan

Propofol

Drug

sedative

Dexmedetomidine

Drug

Sedative

midazolam

Drug

sedative

Saline placebo

Drug

saline placebo

Primary outcomes

  1. Dynamic Eye Movement Measures

    Time frame: baseline to Sedation State (approx. 1 hr)

    Change in Eye Movements Parameters

Sponsors and collaborators

Lead sponsor

University of Alabama at Birmingham

Other

Collaborators

  • National Center for Research Resources (NCRR)

Registry information

Acronym: Eye Movement

Important dates

Study start
2007
Primary completion
2008
Study completion
2008
First posted
Mar 28, 2008
Registry last updated
May 19, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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