The Effect of Sealer Type and Obturation Technique on Postoperative Pain

Postoperative pain is an important consideration in endodontic treatment, and its incidence may be influenced by both obturation technique and sealer type. This study focused on molars to minimize anatomical variability and provide a consistent assessment of pain associated with different endodontic protocols.

This study aimed to evaluate the incidence and level of postoperative pain in molars treated with root canal therapy, in relation to the type of sealer and obturation technique used.

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Key information

Conditions

Dental Pulp Necrosis Bites and Stings Chemically-Induced Disorders Dental Pulp Diseases Necrosis Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Poisoning Postoperative Complications Signs and Symptoms Stomatognathic Diseases Tooth Diseases Wounds and Injuries

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Jordan university of Science and Technology

Irbid, 221000, Jordan

About this study

One hundred and twenty patients (aged 18-60 years; 63 males, 57 females) requiring root canal treatment of mandibular or maxillary molars will be included. Only teeth with necrotic pulp and asymptomatic apical periodontitis or previously extirpated pulp are considered. Patients will be randomly assigned to one of four groups (30 patients each): Group A-AH Plus resin sealer with cold lateral compaction (AH-CLC); Group B-AH Plus with warm vertical compaction (AH-WVC); Group C-TotalFill bioceramic sealer with single-cone technique (TF-SC); Group D-TotalFill HiFlow with warm vertical compaction (TF-WVC). Postoperative pain will be self-recorded using the Visual Analog Scale (VAS) and Verbal Rating Scale (VRS) at 6 hours, 1 day, 2 days, 3 days, and 1 week after treatment. Completed forms will be collected when patients returned for permanent coronal restoration. Analgesic use was also recorded. Data will analyzed using one way ANOVA and Chi square tests.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

both male and female patients within
The age of 18-60 years old who required root canal treatment
Either mandibular or maxillary molars with the diagnosis of either; necrotic pulp with asymptomatic apical periodontitis,
Teeth with pulp extirpated ( previously initiated root canal treatment) regardless of the periapical status

Exclusion criteria

Teeth diagnosed with irreversible pulpitis;
Teeth with intracanal abberations or mishaps such as perforations, transportation, severe ledging , broken instruments, apical resorption or open apices;
Teeth requiring posts;
Any patient on long term steroid or any other medical condition that requires long term analgesic.

Treatment and study plan

Obturation of root canals

Procedure

filling of root canal using different materials of resin based or bioceramic based and cold lateral condensation or warm vertical condenstion techniques

Other names: Root canal filling with bioceramic sealers

Primary outcomes

Pain level after obturation of root canals

Time frame: 6 hours, 1 day, 2 days, 3 days and 1 week

The level of pain the patient will experience after obturation of the teeth using a visual analogue scale and a numerical scale from 0-10. Zero is the minimum and 10 is the maximum. The higher the score the worse it is, the best technique will have low scores of pain

Sponsors and collaborators

Lead sponsor

Jordan University of Science and Technology

Other

Registry information

Official study title

The Effect of Sealer Type and Obturation Technique on Postoperative Pain of Root Canal Treated Teeth

Acronym: pain

Important dates

Study start: 2022
Primary completion: 2023
Study completion: 2023
First posted: Feb 4, 2026
Registry last updated: Feb 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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